Azathiaprine side effects?

[Running44]

Morning all,

I’ve been taking 100g of Azathiaprine for 18 months for AIH which has now been increased to 150g. I can really notice an increase in fatigue and wondered if anyone else has fatigue as a side effect?

thanks all

[AyrshireK]

That seems an awfully big dose - it's usually decided on body weight but I don't get the impression you are overly large.

Fatigue is sadly a common symptom of AIH and some of the meds.

If you do Facebook there is a very well informed private AIH support group on there who can share experiences and knowledge. facebook.com/groups/AIHorgUK

Katie

[Running44 in reply to AyrshireK]

Thanks for your response Katie. You’re right, I’m definitely not large in stature at all. I’ll check out the FB group as it’d be good to connect with others experiences

[Buddythezhu]

I have AIH diagnosed in 2022, I agree with the other reply, join the Facebook group, I find it very helpful. I’d never heard of AIH before I was diagnosed. Fatigue is something I live with and understand it’s a symptom of AIH. I started with Azathioprine but it made me very nauseous so I now take Mycophenolate. I think the fatigue is the AIH not the medication.

[Aztec632]

Hi I take Aza and have fatigue. I am a member of the Facebook group for AIH .

Some people suffer with fatigue and others don't. I am sure you will get a big response if you join the group

[marianne22]

I have AIH, although I am asymptomatic, and I definitely recommend the Facebook group. It's a friendly group with lots of knowledge and advice.

[Katahdin]

I have AIH and have been taking 150mg Aza 19 months with no issues. The AIH groups on Facebook are a great source of knowledge and support.

[LorraineLouise]

I have noticed, hair loss when I first started the drug. Although I was taking mine for rheumatoid arthritis, which helps tremendously. And bonus, it brought down my liver enzymes. Which are always elevated due to primary biliary cirrhosis. I can’t say I am any more tired, while taking it. My hair started to come back after I started folic acid as well.

Hope this helps,

Lorraine Louise

[Contrabass]

Hello running44,

Short reply: think fatigue not uncommon with AIH

Long reply 🫣

I was on 100mg of Aza for over couple of years, increased to 150mg 7 months ago. I have a lot of AIH liver cirrhosis. I do feel fatigued and lack of energy, exercise seems to give a temporary boost 👍. Apparently my red blood cells are bit larger than normal, which strangely(?) means less oxygen carried around - possibly/probably contributes to fatigue.