Amino acid urine test finds taurine “wasting”, elevated beta alanine and anserine - anyone else?

[SkinNBones]

hi. Input much appreciated on a mystery . First background: I have had elevated ALT, AST, and GGT for decades along with poor health and some little recognized chronic conditions. I would like to know if anyone else with liver disease has or has heard of the following odd metabolic derangement. I am wondering if they could result from liver failing to produce the needed (transaminase) enzymes for metabolism of certain compounds

Ok so the mystery concerns “taurine wasting”. I have low taurine levels in blood and in urine its being “ wasted” as can see high levels there. In addition, the cause of the excessive loss in urine is apparent because the beta alanine level is very high. Taurine and beta alinine are structurally similar and compete for reabsorption at renal tubules. A greatly increased anserine (im more likely to eat poutry and fish than red meat) helps clarify the high beta alanine. I know rate limits can gonin both directions so dont know which elevation primary and which the result. I do not have excessive intake of protein or snything else, in fact its less than average and I am very underweight from not fully known causes. Theres no dysbiotic bacteria that might be causing the beta alanine directly.

Anyone else have or heard of any of this? Thanks in advance! I cannot disentangle the metabolic spider web

[BritishLiverTrust1 Partner British Liver Trust]

Welcome to the forum,

This question and some of the others you are asking on other forums really are best answered by your own health care professional, as only they have access to your full medical history.

We suggest talking this through with your own doctor or health care professional in the first instance.

Best wishes

British Liver Trust

[SkinNBones in reply to BritishLiverTrust1]

Thanks for the welcome but everyone else in this forum seems to get all sorts of input from others- why not me?

(I have a zillion docs but I still greatly value input and comments and experiences from other patients Maybe I worded my messages wrong - i am not looking for medical advice- I will work on wording my messages more appropriately; thanks for the heads up on that.

[BritishLiverTrust1 Partner British Liver Trust in reply to SkinNBones]

Members post and reply to offer other members support and share their own experiences if they are similar and could be helpful.

It's possible that no member who has been active in the last day is able to answer your question. Not all posts are able to be answered by members.

This may be one that you do need to speak to your own doctor or specialist to discuss.

Best wishes

British Liver Trust