sorry if it's happened, i am just wondering if it happens as much as the campaigns say it does. thanks.
it's difficult to know the rate of incidence in the past, before drugs, as the current reporting says it happens due to osteoporosis - but in how many of those cases were patients already taking OP drugs? how many of them were due to injury by drugs, and how many were actually from 'low-trauma'?
similarly i know a few people who had a flu shot, got really sick after it, then that was counted as flu, not as caused by the injection. really, this is deception. i have so many questions. can't get honest answers from specialists as their minds can not be changed. they get paid by drug companies. i wonder if they really know the truth? would they prescribe it left right and centre to their loved ones?
You can't get flu from a flu shot because there is no live flu virus in it (except some nasal versions given to young children). But if a person got sick right after the shot (not just a reaction to the vaccine) then supposedly it was because their immune system had not had time to build up the immunity stimulated by the vaccine.
Interesting questions about the bones and probably someone has the answer. Of course most bones break because of accident, not because of bone thinning. As the femur is the strongest bone in the body wouldn't you think it would be the least likely to break spontaneously?
Hi. I will not have flu or covid shots as you call them. In the past I was always ill after the injection. I believe the flu like symptoms I had, were caused by the reaction to ingredients in the shot. I was medically retired in my 40's due to an ingredient in a medication I had been taking. It took 18 months to find the cause of my illness......the red colour "red ponceau"....which then had been removed from sweets yet even today remains in medications. It was the nurse in my practice who solved the mystery, not the doctors or specialists. My doctors did acknowledge the cause and reported my case through the yellow card system which we have here in the UK.
Doctors have to operate within the guidelines of the World Health Oganisation, which is an unelected body which in my opinion has too much and inappropriate power. I believe doctors act in good faith according to their knowledge. I believe Big Pharma is a business like any other and favours profits.
I'm so sorry that your mother's experience is so distressing. Both of my parents suffered also in different ways, and I believe the covid shot killed my sister. We are all different. I know that I lack enzymes which break down various chemicals. Medication prescription really is a trial and error process. What helps one person may harm another and yet we may not know until it happens.
It would be helpful if big pharma was more honest and open about the ingredients in medications. My gp told me the flu vaccine was mostly egg white.....it took a lot of research on my part to track down and find out that one of the ingredients is mercury. ...at least it was at the time I researched it. Big pharma uses several different names for the same ingredient which makes it very difficult to research. Our doctors do not have the time to double check every thing they are told and truly believe what they are taught in their training and guidelines they are given.
It's good that you are questioning, frustrating when answers are not forthcoming and I acknowledge how angry you may be feeling. Regretfully, we cannot change the past, use your wisdom for now and the future and I wish you and your Mum the very best.
Di Doh xx
another thing i notice is that bisphosphonates are getting a bad name, that they cause problems - but what drug preceded them? is that a contributing factor?i reckon. and i could be wrong. there's just so much lying and omission that i have to fill in blanks while partly guessing.
prolia exclude adverse effects of patients taking prolia more than 3 years from their safety / marketing stats (Cummings 2009 NEJM).
my heart is downcast. i stayed away from the boards a few weeks as it became too much. you know what i mean. i should still stay away but have questions again, and info to share.
When I do a search on the NEJM site for “Cummings 2009 Prolia,” I get three hits. It isn’t clear if any of these are the citation you noted. Can you be more specific or provide a link? Thanks!
hi, simply the reference of 36 months which was the duration the trial, anyone correct me if this is no longer the cited study nejm.org/doi/full/10.1056/N...
Feel free to speak to a Specialist nurse on their helpline. They will be happy to talk to you about all of the above comments. 0808 800 0035
i can scarcely say the word fracture, but they get renamed.
prolia-induced fractur gets renamed 'rebound' - but - it's prolia-induced,.
'atypical' is actually typical - typical of OP drugs.
'medication-related' is actually prolia-induced.
side effect is actually a known effect.
the rebound frature isn't induced by the prolia... taking the prolia doesn't cause it...when you stop taking the prolia the body (bone turnover) reacts...you must take something to prevent that ...you need to sort that out with your doc.
yes but it doesnt happen if you never took prolia, i shoukd say prolia-related. or osteoclast resurge following cessation of prolia...
Well, actually, the rebound is rebound osteoporosis which can be worse than the original condition the denosumab was prescribed for, so I'd say Prolia did cause those "rebound" fractures.
I think many (possibly most) have their osteoporosis diagnosed after they break something. Bone density isn't routinely checked unless you have a risk factor, one of which is having broken a bone.
I broke the neck of my femur from the impact of road running without being on osteoporosis meds and only having osteopenia I also broke all my ribs in multiple places with osteoporosis but again I wasn’t on any medication as I had refused to take it.
Since I’ve been on the zolendronic acid infusion I have not had any fractures and I’ve been on it for 21 months.
thanks for telling about it, i feel a bit bad asking about people's pain and suffering so i can gain some perspective. i'm dismayed that marketing and campaign blurb get all statistics and mix them together, the treated and untreated, to put everyone wholesale onto medication, rather than being more selective about who really needs what...
I can only go off my experience and the pain from the breaks and fractures is something I will never forget with the ribs I couldn’t even leave the house for nearly 8 months so I am happy I am having the infusion and it’s improved my t scores my spine is no longer osteoporosis so that’s a massive improvement so the drugs do work xx
Which goes to show that in some cases a bisphosphonate can work very well, and no risk of rebound as occurs with the newer OP drugs. 
The issue with the bisphosphonate occurs when bone remodelling is stopped for too long, and that's when the bones become brittle. I think it's considered a good idea to have a drug holiday after two or three years. Also, do everything you can to rebuild bone strength "naturally"!
That’s what my rheumatologist told me to have 3 infusions one a year then have a break and reassess after that. I don’t have the natural option as I have bowel conditions so I don’t absorb vitamins and supplements etc but I drink a litre of almond milk which gives me my calcium and vitamin D requirements so I’m always in the healthy range for those and I have two walks a day to keep my body moving which helps me physically and mentally.
I feel that what I've been able to do physically has been at least as important as what I eat. But as far as nutrition is concerned, Vitamin K2 (not K1) is really important, because it is what sends calcium to the bones, and if you aren't able to absorb it in a supplement I think there are sprays that can be used, although I have no personal experience of this. Vitamin K2 is very lacking in the modern Western diet.
As far as I know there was no drug before bisphosphonates. My father was just told to drink milk
(oh, i meant what drug was a person taking before starting on bisphosphonates)
Yes, there are some which can contribute to bone thinning. Often mentioned is prednisone, but not mentioned are PPIs like Omeprazole, which if taken longterm inhibit proper absorption of nutrients, and I'm sure there are others.
if a hip bone is broken, without / before drugs, i wonder is it usually unilateral.
and sorry it has hapoened. i may find out for myself, as i have a sore hip bone, sore t vertebra, possibly / likely poor bone health due to lying down for most of the last 15 years, also stressed recently, also thyroid medication here and there.
did have a heck of a fall hitting my head 6 months ago. nothing broken thankfully. i bled heaps. could improve my diet.
Good questions that you are asking but unfortunately, little research done by pharmaceutical companies about long term use and their side effects of said meds. I've been trying to find those studies but companies say it's too costly to conduct said investigations/research and that the meds work. However, what you're asking for is research to answer that question of yours and that's hard to find. Anyone have said info and links to share?
I'd like to refer you to my story. It's a bit old now, in terms of links, and I did read a lot more than I posted at the end of the story. But the basic ideas are still perfectly valid.
endocrinologist told me the statistic that in the first 12 months after a first fracture, the greatest number of bones following occurs .now that is terrible. but - if say 3 vertebra get broken, then there's now fewer bones left from the pool to break, so of course that number will go down from that.
and that teeth seem to not be counted as fractures, it's a crime because they add to the count and have diagnostic / prognostic (indicator) value.
Has anyone had sacral ala (pelvic) insufficiency fracture while on Prolia and/or a bisphosphonate? 
Has anyone had positive results, low side effects with Foxamax? 
do I need medication 
results of X-rays
