Antiarrhythmic drug identified as pot... - Lung Conditions C...

Lung Conditions Community Forum

55,235 members66,012 posts

Antiarrhythmic drug identified as potential treatment for pulmonary arterial hypertension

2greys profile image
4 Replies

High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a potentially fatal disease caused by obstruction of blood flow in the lungs. A new study in The American Journal of Pathology sheds light on the pathology underlying PAH and shows that dofetilide, an FDA-approved KV11.1 channel blocker for the treatment of cardiac arrhythmias (brand name: Tikosyn), may be used for treatment of PAH.

medicalxpress.com/news/2019...

Source research paper here:

ajp.amjpathol.org/article/S...

Written by
2greys profile image
2greys
To view profiles and participate in discussions please or .
Read more about...
4 Replies
nettevaw profile image
nettevaw

I’m taking solidifies it’s generic for viagra to treat my PAH

Offcut profile image
Offcut

Sildenafil, was originally made for heart conditions it was the other affect that then came into use later.

I also have to take Sildenafil 3 x 50mg a day plus Ambrisentan and Bisoprolol. Due another RHC this month at Sheffield to see if I have improved?

Be Well

Offcut profile image
Offcut

It took a few months of feeling proper rough with the Ambrisentan but I have seen a mild improvement. the reason for my second RHC is to see if the pressure has been changed by the medicine so far? I will then need another RHC if they decide to take me off any or change them? They have also concluded I have Precapillary IPAH ? I have not played by the normal rules it seems( Nothing new there?) The first RHC showed only 70% O2 but my blood was 92% at rest? When I had the Nuclear MRI for some strange reason my left lung did not show at all but the regular MRI on the same day did, which at first they thought I had CETPH? I did know after a very grueling day my lungs hurt with all the breathing in and out etc. ;)

The cold hits me hard and mild exercise but stairs are on a better day slightly winding me, but I can struggle another?

BTW. I am WHO Class iii High IPAH

BE Well

Offcut profile image
Offcut

I think my many other comorbidities do not help overall but PMA

Be Well

You may also like...

pulmonary hypertension

found the the letter which said I had pulmonary hypertension and said he had not arranged to...

Pulmonary hypertension & Cor Pulmonale

cope with it and any treatment you are having. I am still waiting to see a lung and heart...

pulmonary fibrosis and pulmonary hypertension.

symptoms and offer any sugesstions as to possible treatments ....

Pulmonary Fibrosis/Pulmonary Hypertension how long?

ability in people with pulmonary arterial hypertension (PAH) or pulmonary hypertension associated...

fibrocis /pulmonary hypertension.

ecgs , someone has mentioned fibrocis and pulmonary hypertension to be honest I’m scared and...