LDL analysis testing

[Winimops]

hi all. My LDL is now 1.4 which is good. But I have had side effects to Rosuvastatin 10mg and my GP has told me to stop them for a month and see what happens to the levels in 1 month. My cardiac rehab team said that I may not even need Statins as it depends what fats are in the LDL. There is a blood teat for this but they didn’t know if it was available on the NHS. The GP wasn’t aware of the test either. I think it is called a LDL particle test.

Has anyone had this test either privately or NHS?

Can anyone shed some light on the analysis and statin therapy please?

I am discharged from cardiology so can’t ask them.

Thanks

[EU95PTM]

I’m not sure if this is the information you are looking for, but there is a test for Lipoprotein(a) which is believed to be an independent cardiac risk factor. The best way to describe it is that it makes the “bad” LDL cholesterol more “sticky” and leads to faster build up of atherosclerosis. It is not something that is routinely tested for in a lipid panel and often has to be ordered via a specialist at a lipid clinic. Many GP’s have never even heard of it so it can be a battle to get. I had this test after having a heart attack at a young(ish) age without any of the usual risk factors (smoking, diet, high BP etc). Now I know why it happened to me as my reading was exceptionally high and was the likely cause of my premature coronary heart disease. Hope this helps in some way.

[Winimops in reply to EU95PTM]

Thank you. That really helps. I will speak to the GP.

[VeganSelfExperiment]

Greeting Winimops,

I just did quite a bit of research on lipids and have asked my previous doctor to send all my vital test results of the previous decades to review. Apparently, the numbers tell a relationship story of pre-diabetes and pre-heart attacks.

Please double check everything I share.

First though, never take a lipid test if you have an infection or your thyroid is off, according to Prof. Dr. Lustig (Understand your cholesterol Panel free video) Chances are that as a female, your thyroid is off (Dr. Wiliam Davis, DIY Thyroid: Part 1-3 free videos). If you have no infection and your thyroid is good, then proceed and take a lipid test.

Second, high triglycerides are 1.8 risk of heart attack, whereas LDL is only 1.3 risk. Check your TGs first. TGs can be lowered quickly (10 days) by no added sugar or sugar substitutes and no wheat products at all (except whole wheat berries which are hard to find).

An LDL of 1.4 mmol/L is 25.2 mg/dL (Formula to calculate mg/dl from mmol/l: mg/dl = 18 × mmol/l). Human babies are born with an LDL of 30-70 mg/dL which is our physiologic number. You might want to ask your GP why he had you on so much medication that you went under human physiological numbers. Ask him what low level of LDL is deadly? Another question is did he test directly for LDL or is it roughly calculated? The two numbers can differ quite a bit. An APO B test is now used in lieu of LDL. Apolipoprotein Evaluation Test has biomarkers ApoA+ApoB, #91727 for $38 USD at ulta lab.

An ideal LDL number to aim for is 70 or lower, but probably not under 30 unless you have some rare genetic disease that they told you about? At 70 and lower, plaque is not added to arteries. Remember, you do need cholesterol for energy and normal body functioning.

EU95PTM discusses the Lipoprotein(a) test which only needs to be taken once if you do not have it and is a good genetic test to take. Briefly as to ranges, 0-30 nmol/l is Low Risk and >50 very high risk according to Lipidologist Tom DaySpring; Desirable: (< 35 nmol/l) in general; Dr. PeterAttia says < 50 nmol/L; and Dr. Davis says correct hidden causes if it is 75 NMOL/L or more. It is the Strongest Genetic Cause Of Heart Disease - Lipoprotein(a), according to New Zealand Dr David Sinclair who says about 25% of people have it. Look into niacin (yup cheap niacin, if you have high Lp(a) and high sd-LDL. The Lp(a) test costs about $30 USD at direct to consumer (no prescription needed) ulta labs.

The LDL particle test is part of the Cardio IQ™ Lipoprotein Fractionation, Ion Mobility test which at one time was very expensive, but now can be obtained by ulta labs for $32.76 USD under weekly specials. Current doctors run this test BEFORE prescribing a statin. You can have significant LDL, but none of it is the deadly small dense LDL - so no statin is indicated. You will get 6 biomarkers in the test: HDL Large, LDL Medium, LDL Particle Number (LDL-P), LDL Pattern, LDL Peak Size, and LDL Small (sd-LDL).

Drs. Mercola and Attia believe LDL-P is a much more accurate predictor of CVD risk than either LDL or total cholesterol. "If you want to stop atherosclerosis, you must lower the LDL particle number. Period." Attia Between 600-700 NMOL/L Drs. Davis and Ozner say you are Heart Attack Proof. Here are other ranges 1409 nmol/L High Cardio IQ.

The sd-LDL is critical and 0 - 35 mg/dL is Optimal Result according to healthmatters.io. Here are some ranges: Optimal 219 Cardio IQ.

LDL Peak Size Optimal >222.9; LDL Pattern A is preferred.

Hope this helps you be the CEO of your health and please double check what I wrote (and what your doctor is doing). (Actually, I re-read your post, and please consider getting a much more competent GP.)

Cheers and good going by being on top of your health and asking questions.

[Winimops]

thank you so much for all the info! I will look into everything you have mentioned.