Mrs Ben

[A246]

I had my three month scan and I was advised that entresto had stabilised my heart failure. However it had not shrunk my left ventricle as was expecting. Only been on the medium dose for three months as could not tolerate the highest dose. Could anyone please tell me if they had good results with entresto after six to twelve months in terms of improvement in ejection fraction as I had no improvement there either, thank you.

[Pouchielou1972]

Hello there,I was told when I first went on heart meds that it can take several months or even several years to see much improvement, it depends on how your heart responds.

I am on the highest dose of all the usual heart failure meds. It took a little while for my body to get used to Bisoprolol in particular, as it made me constantly exhausted, but that seems to have subsided.

It took 9 months for my EF to go from 10% to 45-50%. Hopefully I will see further improvement in the months/years to come. Entresto was a game changer for Mr.

Please just bear with it, as 3 months is extremely early to see much change with heart meds.

[A246 in reply to Pouchielou1972]

Dear Pouchielo 1972 thank you very much for reply very much appreciated x

[Barre01]

I am on the medium dose of Entresto, my EF has improved from the low 20s to high 30s.

[A246 in reply to Barre01]

Dear Barre01 thank you for your reply very much appreciated x

[Grasshopper1976]

Hello A246, I was diagnosed with HF in August 2023, I am on Entresto 24/25mg which is my starting dose, I expect the dose to increase. I've had 24 hour ECG, ultra sound and Friday jus gone had MRI. And today I have an appointment with Consultant where I am too get results and full diagnosed. Currently taking Entresto, bisoprolo 2.5 mg and dapaglifozin 10 mg. And at present their are know side affects. Been on the meds less than 6 months . And hoping my ejection fraction has improved I feel a little less tired and fatigued and my ECG heart rate has balanced and keeping me in sinus rhythm. Should have more answer's this afternoon.

Best wishes

Peter

[A246 in reply to Grasshopper1976]

Dearest Peter, it seems we were diagnosed at the same time mate. Thank you for your reply very much appreciated. How did you get on buddy. I am now waiting to have an ICD fitted. Best wishes Lynn x

[Grasshopper1976 in reply to A246]

Hello , ok the ultra sound put my EF at 35%, but the MRI put EF at 51% . And my symptoms are mainly tiredness and fatigue and shortness of breath after rigorous activity. I have an appointment with consultant 7 th February, too find out more information and where MRI results put me. I am staying positive. My consultant did say if my EF remaind, 35 % or less, I would need ICD. Hoping everything goes well, try not too worry to much. The ICD is a good device.Thank you for your message.

Best Wishes

Peter

[A246 in reply to Grasshopper1976]

Dear Peter, your EF results are fantastic buddy so very happy for mate. Your symptoms of tiredness and exhaustion on vigorous exercise may improve over time with the meds you are on buddy. Please can you let me know how you get mate. Great news. Best wishes Lynn x

[Grasshopper1976 in reply to A246]

Hello Lynn yes I am hoping things improve with meds, At present I sleep when Exhausted, can't stay awake. But sleep is important, so I'll take that on the chin. How is your health at present, hope your not too unwell. I will keep you updated and share how things are going.Great to chat with yourself having the same condition . Support and a welcome ear is always here. Take care stay positive

Best Wishes

Peter

[A246 in reply to Grasshopper1976]

Hi Peter, glad to hear that you are getting your rest when needed buddy. I am stable awaiting ICD ATM. I am hoping to back to work as soon as ICD done and after waiting period. Thank you for your support mate. Support here for you too. Lynnx

[Grasshopper1976 in reply to A246]

Hello Lynn glad your stable , hoping your ICD is being done soon and helping you get back too work. It's wonderful when you can do something others take for granted. Support and talking is in powering and a great a positive thing, for us.Thank you for your wisdom and support , Lynn, support and understanding makes for a great friendship.

Take care for now.

Best Wishes

Peter

[A246 in reply to Grasshopper1976]

Dear Peter, thank you for kind support buddy really appreciate it. I think I will get ICD done next week. I have a post op assessment on Thursday. Things are happening now, just want to go back to work. I wish you all the best too mate, and hope that you too and everyone in our position gets well again. Thank you. Lynn

[Grasshopper1976 in reply to A246]

Great news, next week can't come soon enough in our situation stuff needs to happen soon as possible, we can live our lives more productively and with less worry and stress. Really is fantastic news. We'll sorry to say but it's getting late, I am off to sleep, wishing you a goodnight. Sleep well. Night.

[A246 in reply to Grasshopper1976]

Hi Peter, hope all is well with you dear friend. I got my ICD in now. Was very sore at first but ok now. Surgery was ok went well. Feeling safer with ICD TBH. Cheers buddy. Lynn x

[Grasshopper1976 in reply to A246]

Hello Lynn yeah iam good and well. Been busy with work. Glad too hear that the surgery went well, yeah the pain must of been difficult for you. And nice to hear your on the mend. Yeah the ICD, definitely good option and you feel safer. Like the good news. Stay well.

Best Wishes

Peter

[Deejay62]

Hi I am on medium dose for 5 yrs my EF was 10% it is now around 23% as of last year, but I have dilated cardiomyopathy and pulmonary hypertension. Some have actually come out of heart failure on it, and the cocktail.

[A246 in reply to Deejay62]

Dear Deejay62 thank you for your reply much appreciated. I too have a dilated cardiomyopathy, my EF is 25 ATM too. As you say these drugs take time to work xx

[BicuspidBloke]

I'm on the low dose and went on to it about 9 months (I think) after my OHS operation My Ejection Fraction was up to 55-60% by 12 months (from 20-25%). However, that's mainly down to the operation & exercise with a little contribution from the drugs (including my previous drug to Entresto, the name escapes me right now).At discharge time (about 12 months too) I asked about my enlarged Left Ventricle and whether that had reduced. The doctor said "it must have been massive before because it's still big!" which made me laugh.

I was warned before the op that the heart is like an elastic band, it can stretch a fair bit and return to normal but it can also stretch too much & for too long and never return to normal. I suspect this is where I am. I asked about what happens next and the Heart Failure Nurse said it can take a couple of years to settle down and they’ll monitor it - which sounded like a fob off (unusually so for the excellent Heathcare Professionals that I've had). I'm not sure how they will monitor now I'm discharged either.

I'm just hoping that continued drug-use and exercise will reduce the LV a little.

[A246 in reply to BicuspidBloke]

Dear BicuspidBloke thank you for you reply very much appreciated. I so happy that your surgery has improved your heart ef function buddy. You have been through a lot to get there. My EF is 25 ATM. I have a leaky valve but I was told it not a problem ATM. So carry on with meds ATM as I am stable. I wish you well for future. Lynn

[A246]

Dear pinkkizzie thank you for your reply very much appreciated. My EF is 25 too. The main thing is that we are stable, best wishes. Lynnx

[A246]

Dear pinkkizzie, thank you so much. It was a lonely journey mate. This site has made a big difference to me too. So many kind people with same or similar conditions to share with and help if we can.. stay well too my dear.