Lisinopril twice daily?

Just wondering if taking my lisinopril tablets half in the morning half at night help with side effects. I have discussed with doctor and it seems to be a try and see approach,I was on 25mg spironolactone and my potassium went up to 5.9. Iam now on 12.5mg and the potassium came down to 4.5. Just wondering if other members do this.

[MichaelJH Heart Star]

There is no problem at all doing this. Mine is actually prescribed morning and evening. I was actually down to 2 5mg when I dropped down to 72kg, 5mg at 90kg and now 20mg at 100kg. Mind you it is really another story and I am still only overweight!

Twice daily...

[Hidden in reply to MichaelJH]

Thank you for the reply. The photo is most helpful. It is the one thing I hate about tablet you take them to improve one problem and other issues come along like buses. Thank again.

[Shar28]

Hello, my husband split his Lisinopril morning & evening and found the side effects were more manageable.

[Hidden in reply to Shar28]

Thank you for your reply. I will have ago and see out it works out. I hope your husband is feeling more normal, by splitting his tablets. I appreciate the reply.

[JessicaRed in reply to Hidden]

I do this too 5mg am 2,5 teatime

[fishonabike]

your GP should be able to prescribe an alternative to lisinopril if the side effects are bothersome -you could check with your pharmacist for suggestions then return to your GP with the information

Lisinopril is an Angiotensin-converting enzyme inhibitor (ACE i) and these are often the drug of choice because they are cheap - there are other medications which have the same therapeutic effect, with different side effects, but are more expensive

[Hidden in reply to fishonabike]

That's a good idea. The thing is when my cardiologist first put me on a blood pressure drug it was losartan. Then it quickly got changed to lisinopril. Never really asked why. So I don't know if lisinopril is causing some of the side effects I have. The only trouble is my anxiety is through the roof and this can cause weird feelings similar to what is noted in the medical explanation of the drug. The trouble is that both lisinopril and spironolactone have done their job according to my cardiologist. But both medication raises potassium and that has been sorted by reducing spironolactone by half a tablet a day. I suppose iam lucky that I am only on two tablets a day. But it seems so hard to find out what is causing what. You just carnt really just stop and see. But when you do ask a question it can sometimes be like how long is piece of string? All I know currently is that lsinopril helps the pumping mechanism of the heart. And spironolactone reduces any water that you may be holding onto around the heart and lungs. Even though I don't have heart failure, due to my congenital issue my right ventrical is not very efficient. But I will try and find something that will help me feel normal, well normal for me that is.

[fishonabike in reply to Hidden]

losartan is an ARB (Angiotensin receptor blocker) , these are the first alternative to be selected if ACEi give problems - from what i heard, they do much the same job but are more expensive, which is one of the reasons for GPs prescribing them less frequently than ACEi

[Hidden in reply to fishonabike]

Thank you for the reply. So in theory does losartan have less side effects than lisinopril? It is a hard one to explain because I was only on losartan for a couple weeks then it was changed. So I don't really have a way to compare.

[fishonabike in reply to Hidden]

i'm afraid i don't know for sure, but from what i've heard the side effects are different - i changed after Ramipril gave me a terrible cough, I have had not noticeable side effects from Losartan - i just feel that if side effects are affecting my quality of life and there's an alternative i want to try it - just because you are affected by side effects from one drug does not mean you will also suffer side effects from a different one, unless you have mast cell activation syndrome

[Hidden in reply to fishonabike]

I see what you mean it is a bit of a trial and error to get the right combination. Thanks for the reply

[VikingWay]

Felly12, Spironolactone was not the answer for me. Eplerenone is better, but not the ultimate solution, either.

[Hidden in reply to VikingWay]

If you don't mind me asking what side effects did spironolactone give you. Unfortunately my congenital issue could be a one off in our family but that's not to say there could be some inheritance. From past. Thanks for replying.

[VikingWay in reply to Hidden]

My doc kept upping the dose, and It was causing 'emotional 'melt-downs'. Not fun!

Dosages went from 12.5mg to 25mg to 50mg; which EACH is a doubling. (My doctor kept telling me to 'up the dosages', and I kept feeling worse and worse; so I took it upon myself to reduce the dose to 37.5mg, which is 3/4s of 50mg, which was a bit of an improvement, but getting switched from Spironolactone to Eplerenone, helped, more. I also take an adaptogenic herbal formula product called "HPA - ADAPT" by 'Integrative Therapeutics', That seems to help with the excessive cortisol problems, with which I am 'plagued'. I seem to have some sort of 'cyclic' problem; maybe it is what the University of Bermingham calls "Connshings Syndrome", as opposed to Conn Syndrome, or Cushings Syndrome. I have a condition called Hyper-Aldosteronism, which causes HTN and debilitating emotional upsets, especially every-other-day. It's a weird cycle! I hope that is not what you have! I do hope that you find a workable, pharmaceutical solution. Best wishes to you!

[Hidden in reply to VikingWay]

Thank you for your reply. Funny things is that when I went to 12.5mg I do feel a little better. Regarding dizziness but as you say I will see if I can find a work able solution. I think I will need some sort of diuretics. But which one?