Edoxaban

[Buttongirl]

I have been prescribed 60mg Edoxaban to take as doctor seems to think I have a stroke risk of 2 and will be 67 on January. I have AFib and on bisoprolol.Just a little worried, should I be?

[Chappychap]

I'm puzzled by what you by a "stroke risk of 2"? I'm reasonably familiar with the main heart/stroke risk measurements that are used in the UK, but that's not something I've heard of.

I have however heard of a stroke risk calculation that has a base line of a 1.9% risk of a stroke each year, commonly quoted as a 2% annual risk, maybe that's the figure you're referencing?

Incidentally, there are two risk factors for strokes that pretty much dwarf everything else. First is age, which we can't do much about. But then there's blood pressure, which happily we can do lots about!

I found that medication, weight loss/exercise, and reducing salt in my diet all reduced my blood pressure by roughly the same amount. Taken together these three initiatives took me from high blood pressure to well down into the safe zone.

If you're concerned about stroke risk (as any sensible person on this forum should be!) then applying yourself to reducing your blood pressure would be a massive practical help towards reducing your risk.

Good luck!

[Motorman]

A Fib is a know risk factor for clots/stroke. So an anti coagulant is normally prescribed. I take them although my A Fib has been sorted by cardioverion, the cardiologist says I will be on them for life.

[Gumbie_Cat]

There is a scoring system to decide if anticoagulants would be beneficial for preventing strokes due to atrial fibrillation. There are points added for different risk factors such as age, sex, blood pressure, diabetes etc.

You are probably the same as me - scoring 2 for female and over 65. This is the score that ‘tips the balance’ in favour of anticoagulants.

[Dadtoalad23]

CHADvasc2 score … 1 point for being female 1 point for being over 65. Anything 1 or over is considered for anticoagulation.

[Huwhuw]

I am 67 with arrhythmia and occassional high heart rate (sometines 150bpm) and have a risk of 1. I take 60mg edoxoban snd 1.25mg bisoprolol daily. My Dr said I had the choice to take an anti coagulant or not as there were pros and cons for me I decided to go.on it as I live in Sri Lanka in the central Highlands in a remote hill village - 1h 30m down a rough road to reach the hospital should I have a stroke. However I have had no bad side affects from edoxaban except for a longer bleed time when I get a leech bite.It's a matter of weighing the risks. I chose to have it due to my.poor access to hospital in an emergency (ie a stroke) Even though my Chas score was only 1.

Good luck

Dave

[Buttongirl in reply to Huwhuw]

HiI think what bothers me is I take 7.5 bisoprol daily and from what I have seen on here my dose us high compared to others! It may be something to do with the fact that I had open heart surgery as a child. AF is well controlled and I very rarely get episodes. Thank you for your comments, again. Very helpful.

Stay well

[Dave678]

I’ve been on 60mg of Edoxaban daily since last Sept with no issues. It replaced Ticagrelor & Aspirin + one good effect is that I don’t bruise as much as I used to do. Plus, had some dental implants recently and was told to just come off Edoxaban two days prior to work whereas with Ticagrelor etc I suspect they would’ve said do you really need the work doing ? PS…I too have slight AF symptoms + take Bisoprolol, Atorvastatin, Entresto, Epleronone, Dapagliflozin & Epleronome.

[Buttongirl in reply to Dave678]

HiThank you for your reply, it's very helpful. I think I am just over worrying.

[Hidden]

no don’t worry. I am 77 chad score 4. No problems with Edoxaban Have changed from bisoprolol to verapamil and seems to have settled things down. Good luck happy healthy new year !

[Hidden]

ps. 10 days post op for hip replacement as well 😂

[ILF1]

I take 60mg Edoxaban and 7.5mg Bisoprolol for AFib (ablation 2.11.2022 and a few blips) and am doing well on these tablets. No problem taking both although it took a while to get used to the Bisoprolol.

Hope all goes well 😁

[Buttongirl in reply to ILF1]

Thank you. Its nice to see someone on same dose, in a nice way. Thank you for replying

[VelvetSky]

Hi, I’m 75, female, HA 2019, stents, I changed to Edoxaban, also Candesartan, Eplerone, Famotidine and occasional Furosemide, not Bisoperal as Chonic Asthmatic. So far so good.

[Silvasava]

I'm 76, female, stroke 2019. I've been on Edoxaban since then and initially 10mg Bisoprolol, changed to Nebivolol. No issues with Edoxaban, just had to stop a couple of days before a tooth extraction. No issues with that either.

[Hidden]

Not particularly-its a safety blanket to help prevent stroke. Age is the most relevant factor-I'm 77 and carry on as normal after a n episode of AF after which I was prescribed Edoxaban. I take an electrolyte tablet twice a day, as my AF was caused by low potassium and magnesium. My sodium levels are always below the average minimum.

The sinus rhythm is triggered by a cocktail of minute amounts of electrolytes being released in precise 'firing order', so if I make sure my electrolyte levels are optimised, I hope I won't get a problem.

[Harrythmia]

I believe another factor to consider in addition to age and gender is family history. I think this already does or should be taken into account in calculating your CHAD score.