Isosorbide mononitrate

[momander]

is any one here on isosorbide mononitrate tablets? I have been on them 2 weeks now and am experiencing what feels like heart burn or indigestion? does any one else experience this at all?

[Hidden]

I took them daily for seven and a half years with no issue.

[nilmonisikdar40]

Heart burn itself is a sign of ischaemic heart disease because the inferior side of the heart and the centre part diaphragm is supplied by vagus nerve. I suffer from heart burn and when I asked a cardiologist, he concurred with me. Does your heart burn go away by taking PPI like Omeprazole?

[momander in reply to nilmonisikdar40]

Hi,Yes, I am on lansoprazole as you can't , or shouldn't take opeprazole with clopidogrel. When I take it, the sensation goes away

[Challenger2009]

I take Isosorbide mononitrate along with a few more, and also get that heartburn / indigestion feeling aswell as nausea but sure most of it is down to the condition

[momander in reply to Challenger2009]

Hi Challenger 2009Do you take anything for your heartburn?

[Challenger2009]

I take Lansoprazole in the morning with my other tablets, sometimes it seems to make a difference other times it seems to make no difference, but I take it anyway as I do wonder if sometimes it's indigestion or chest pain.

[Celticfc1974 in reply to Challenger2009]

I'm on isosorbide mononitrate as well and suffer from severe heartburn. I have ischemic heart disease and severe aortic valve stenosis awaiting surgery. Every pain I get I think I'm having a heart attack and it's driving me crazy. I'm also on metformin which also gives me heartburn also. I'm also on lansoprazole as well. Makes a difference one time and then not the next. I feel like a walking wind bag all day everyday. Kind regards David

[Buzzy-Beans]

I was prescribed this woeful drug some time ago and after haven taken it for only a few days I started to experience quite a few of the well known side effects that are detailed in the leaflet that comes in the packet.This was prescribed by the consultant at Papworth, however on talking to my GP, she put me onto an alternative drug.

I would suggest you speak to your own GP asap and don't accept any suggestion that you need to also be taking an anti acid medication as there are alternative medications to Isosorbide Mononitrate which do not have the same side effects.

[momander in reply to Buzzy-Beans]

Hi Buzzy-Beans,Thank you!

I managed to speak with a gp this morning ( not my usual one) but she is phoning me back next Monday. Basically I was told to come off the isosorbide mononitrate and double up my lansoprazole until Monday. Conflicting views from so many different GP's, as one says this medication will help my intermittent chest pains, another says it wont, and I shouldn't be on it?, another says its for exertion angina only and not resting angina??? as far as I know I don't have angina? or have not been treated for it??? I had a heart attack and a stent fitted last April, but began experiencing chest discomfort a few weeks ago. One GP said the gtn spray and the isosorbide mononitrate are there to help open the blood vessels in the heart and allow oxygen to flow easier!? I get that but some doctors are saying a heart attack is a form of a cramp or a stitch in the heart and it is called angina??? other doctors say they are 2 different things??? it is very worrying and confusing not knowing what is correct?? I am very lucky with most medications but sometimes I find a tablet that just doesn't suit me

[Buzzy-Beans in reply to momander]

Unfortunately I have reacted badly to several of the meds. prescribed for me over the past 4+ years since my troubles started!

I am exceptionally fortunate that if I need to speak to one of my GP's about one of my issues then generally speaking I am able to do so, if not immediately, then within only an hour or two. I have built up the same level of contact with all 3 of the consultants I am under in Cardiology, Respiratory and Ear Nose & Throat. Although my initial contact is with their secretaries (darlings the lot of them), if my contact is felt to be important then generally speaking I am able to speak to the consultants within only a few days, and YES this is with the NHS!

Obviously your main line of attack is with your GP and when it comes to them, don't take no for an answer from their frequently damnable admin and secretarial teams!!

[momander in reply to Buzzy-Beans]

Hi Buzzy-Beans

After my heart attack and subsequent stent last year, I was told I only had a small ammout of plaque, hence the stent, and other wise, a healthy heart with no signs of any disease. Fast forward 10 months and I am feeling pains in my chest again and sometimes jaw pain. I m waiting to see a cardiologist, which I am very grateful for. It is a worrying time, and I know there is something wrong, I just don't know what at the moment. Everyone keeps telling me to stay calm and try to relax!!! really not that easy just now!!! I know there are many people much worse than me but I am really quite worried. I guess its the not knowing and the chest pains still being there!!

[momander in reply to Buzzy-Beans]

Hi again Buzzy-Beans,I would be interested to know what alternatives there are to isosorbide mononitrate? I m speaking with my own GP next monday and would like to have some of my own suggestions for her!! something that does not cause this awful burning sensation like heartburn

[benjijen]

I have been on 60mg and have been for several years. It should be taken alone without food. The only problem I had was when it was reduced to 30mg and my angina returned with avengance! I'm on plenty of other drugs including lansoprozol.

[WardijaWardija]

I've been on Isosorbide 60mgs alongside Omeprazole 40mgs and Clopidogrel 75mgs (plus many more), all taken in the morning, for over 2 years. No adverse issues at all. Cardiologist has no plans to change them.

[momander in reply to WardijaWardija]

Hi,Gosh, you are lucky!!!! I was advised not to take omeprazole with clopidogrel as it can reduce the effect of it. I now take lansoprazole. I only found this out on this forum!!! I guess all doctors and cardiologists are different. Mine took me off it straight away when clopidogrel was prescribed

[dunestar]

I take 30 mg extended released every morning. For me it's made a huge positive difference to the management of my microvascular angina. I've not noticed any impact on my digestion and I've got a hiatus hernia plus acid reflux.

[momander in reply to dunestar]

Hi,You are so so lucky to have no problems. I guess its just the way my body reacts to it. Stay well

[Rostom]

Taking 30mg for angina for over a year with no ill effects at all.

I take this two hours after steroids for another condition which in turn are taken 40 minutes after Lanoprazole and an hour before a tranche of other pills.

It's possible that my earlier Lanoprazole is still protecting my stomach but can't be sure - am not a chemist!

Why not explain your symptoms to your GP (a telephone consultation would suffice) and see if there is something that would help you?

[momander in reply to Rostom]

Hi,I spoke with my GP today so just coming off them then waiting to see what else we can try

[Ghost-233]

I’m on this drug as well as many others. My indigestion actually improved when I went onto Isosorbide, when I began taking it I gradually increased the dose over 2 weeks. I’ve been on Pantoprazole for many years my Gastro Consultant advised me to take it at least 20 mins before eating.

[momander in reply to Ghost-233]

Thank you!!! I think i am just unlucky with this tablet. stay safe

[Rostom]

Good, glad you sought his advice! Good luck.

[Angina53]

Hello, I have been taking 60 mg of Isosorbide Mononitrate for a couple of years without any problems but I'm also now taking Ranolazine 375 mg and have had a few bladder issues. Is anyone else on Ranolazine?

[Suzyh in reply to Angina53]

Hi iv been taking it for a couple of months no problem chest pain a lot better

[momander]

Hi,You are one of the lucky ones!!! I guess we re all different when it comes to our tolerance of certain medications

[Hidden]

I have had gastro reflux disease for nearly 15 years. It has been controlled adequately by esomeprazole (Nexium) up to my NSTEMI cardio event 4 years ago when my meds were changed to lansoprazole, due to the adverse reaction Nexium would have had with my heart meds, and so I have rarely had 'indigestion' in recent years. Last week I was diagnosed with angina following a trip to A&E, and in addition to all my other meds I have been prescribed as a starter, slow release 30mg isosorbide mononitrate in the morning plus 2.5mg Ivabradine 2x daily . Headaches apart I have had what can only described as 'indigestion' discomfort since taking these meds, which is worse during the day so I am putting that down to the nitrate. As a newcomer to angina it has been difficult these last few days differentiating between angina and digestive system disorders, although I now believe it is all down to the nitrate causing 'indigestion'. That said today is the first day, so far, where I haven't had much 'indigestion', so I may have turned the corner. Hopefully the headaches will follow which I am also putting down to the nitrate

[momander in reply to Hidden]

Hi LowerField,I ended up phoning NHS 24 and was advised by a GP to come straight off the isosorbide mononitrate. It is not for everyone and for me it just was not worth the pain and discomfort I understand what you mean when you say it is sometimes hard to know whether the pain/discomfort is heart related or not!? It sometimes is quite difficult isn't it

[Hidden]

I have issues with both of the angina meds I have been prescribed. I have headaches and more than likely gastro problems from the nitrate as I explained, and possibly headaches plus heart rate lowering from the ivabradine. When I was initially prescribed the ivabradine by the cardio man at the hospital I explained that my resting heart rate was normally 55-60 but was told to try it even though the recommendation is to only prescribe for people with resting heart rates of >75bpm. Consequently my heart rate can drop to the lower 40s bpm when I am asleep at night (I wear a Fitbit type device). I have a hospital review in six weeks time but may have to give my GP a kick for a review before then if matters don't improve. The worse case scenario is I just wean myself off these meds for the time, and take my chances, until I have the hospital follow up. I have already made some life style changes which may help me both short and long term.