Can anyone please tell me is it ok for me to up my seritide to 500 from 250 for a bit as PF is getting down to 300 at night and about 325 in am. My best is 400 and norm around 370-380. I have rung and left message for asthma nurse at costa but no one has rung me back. I have upped ventolin and am using it 4-5 times a day but still get a bit wheezy after walking etc which I don't normally have a prob with. Is it ok to up it myself or should I wait for someone to contact me?