Nano-sized particles have been engineered in a new way to improve detection of tumors within the body and in biopsy tissue, a KTH research team reports. The advance could enable identifying early stage tumors with lower doses of radiation.
In order to enhance visual contrast of living tissues, state-of-the-art imaging relies on agents such as fluorescent dyes and biomolecules. Advances in nanoparticle research have expanded the array of promising contrast agents for more targeted diagnostics, and now a research team from KTH Royal Institute of Technology has raised the bar further yet. They are combining optical and X-ray fluorescence contrast agents into a single enhancer for both modes.
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ACS Publications. Research Paper: