Whether vitamin D can reduce the risk of infection is a still an open issue. Four years ago, a synthesis of current research was published that showed that vitamin D supplementation can provide a certain degree of protection against respiratory infections.
Now, the same researchers from, amongst other institutes, Karolinska Institutet, Harvard Medical School and Queen Mary University of London, have expanded the earlier material with an additional 18 studies and carried out new analyses.
Their results are based on 43 randomised and placebo-controlled studies on the possible relationship between vitamin D and respiratory infections involving almost 49,000 participants.
The material the researchers have drawn on comprised published as well as registered but as yet unpublished studies, and is the most comprehensive such compilation to date.
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The Lancet. Research Paper: