Researchers have for the first time identified the way viruses like the poliovirus and the common cold virus ‘package up’ their genetic code, allowing them to infect cells.
The findings, published today in the journal PLOS Pathogens by a team from the University of Leeds and University of York, open up the possibility that drugs or anti-viral agents can be developed that would stop such infections.
“This study is extremely important because it shifts our thinking about how we can control some viral diseases.” Professor Peter Stockley, University of Leeds.
Once a cell is infected, a virus needs to spread its genetic material to other cells. This is a complex process involving the creation of what are known as virions – newly-formed infectious copies of the virus. Each virion is a protein shell containing a complete copy of the virus’s genetic code. The virions can then go on and infect other cells, causing disease. What has been a mystery until now is a detailed understanding of the way the virus assembles these daughter virions.
leeds.ac.uk/news/article/47...
PLOS Pathogens. Research Paper:
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