cri.utsw.edu/researchers-un... at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered a new metabolic vulnerability in a highly aggressive form of non-small cell lung cancer (NSCLC). These findings could pave the way for new treatments for patients with mutations in two key genes – KRAS and LKB1. Patients whose tumors contain both of these mutations, known as KL tumors, have poor outcomes and usually do not respond to immunotherapy.
“We used to think that most tumors rely on the same handful of metabolic pathways to grow, but we’ve learned over the last decade that this is an oversimplification. Instead, different tumor subclasses have particular metabolic needs arising from mutations in key genes. Understanding how specific combinations of mutations promote tumor growth and metastasis may allow us to design tailored therapies for patients,” says Ralph DeBerardinis, M.D., Ph.D., a professor at CRI and a Howard Hughes Medical Institute investigator.
Hi all I'm newbie. Anyone here have lung damage due to Amiodarone treatment?
New drug approved in Europe for uncontrolled COPD. 
