T-cell abnormalities in severe COVID-19 cases.

[2greys]

There is an idea within the coronavirus research field that there is some kind of T cell abnormality in critically ill COVID-19 patients, but specific details have not yet been clarified. To shed light on the problem, a research collaboration based in Kumamoto University (Japan) has performed a genetic analysis of T cells from lung tissue of COVID-19 patients. Their work revealed abnormalities in T cells that resulted in overactivation that may cause severe pneumonia. The researchers believe that their findings will lead to new ways of avoiding severe pneumonia caused by coronavirus infections.

COVID-19 continues to have an enormous impact on daily lives. Why some people become severely ill while the majority of those infected are asymptomatic or very mildly ill is still a major unanswered question. Risk factors for severe disease include old age, diabetes, obesity, and hypertension. We also know that critically ill patients experience an increase in inflammation factors (inflammatory cytokines) and immune system overreaction, whereas the number of T cells, the “command centers” for immune cells, is significantly reduced in the blood. However, the medical implications of these findings are still unclear.

bioengineer.org/t-cell-abno...

Frontiers in Immuniolgy. Research Article:

frontiersin.org/articles/10...

[Alberta56]

Your findings are always interesting.

[blueskies--2]

Yes your finding are very interesting , but to understand it would be useful. Maybe at a later day as you say.