Biosimilar drugs/ injections.

[Luludean]

I wrote to the person today about biosimilar drugs. But my post disappeared!!!!!

I know no one else on these and would like to communicate.

I was on Adalimumab but after a year of constant UTIs stopped . Now I’m weekly injecting Benepali. I now have nosebleeds and horrid acid reflux.

My GP practice will not discuss anything to do with Biosimilars/ Biologics . This is very unsettling , I have persistent AF also , so, on a cocktail of heart pills as well . I feel toxic

Would love to share information . I’m on Cambridge. Louise Dean

[Batty1]

Im on Cosentyx and Otezla for psoriatic arthritis and the only issue I have suffered with for the past 4 years while on Cosentyx is allergic reaction issue after injections (itchy, painful injection lump and injection bruises that last for weeks).

drugs.com/sfx/humira-side-e...

[Luludean in reply to Batty1]

I’ve never heard of those 2 drugs. Are they biologics?

Do you have psoriasis on your skin ? I don’t but they say I have psoriatic arthritis .

O….. and lots of other similar things . L

[Batty1 in reply to Luludean]

Both are biologics Cosentyx is a (injectable) Otezla is a (Pill) but both work very different.

Yes I have both psoriasis and psoriatic arthritis and just because you don’t have the skin issues doesn’t mean you can’t get psoriatic arthritis especially if psoriasis run in your family.

Do you have a family history of psoriasis?

[Luludean in reply to Batty1]

Hi Batty , there is no psoriasis in the family. I was also told at one time that I had Polymyalgia and Sjorgens. Makes my head spin

[Batty1 in reply to Luludean]

If you don’t have a family history of psoriasis then its very unlikely you have psoriatic arthritis unless you have someone close in family that has psoriasis and it just hasn’t been something they talk about or even familiar with because it could be a mild case and easily be mistaken for eczema.

[bernie64]

Hi sorry to hear your not well. Do you get your injections through the hospital? I would contact them to discuss problems. Like you my gp refuses to answer any questions about this. Hope you feel better soon and get answers from the hospital

[Luludean in reply to bernie64]

Thanks Bernie, I feel ok , just unsupported ! Injections come in car , ordererd by hospital provided / delivered by a care company. I can leave queries on hospital phone, they take 5 days to get back . I just keep having changes, headaches, nosebleeds, dry skin and acid reflux. I need trassurance or to SEE someone. L

[Lizzyear]

Sorry to hear you are not having a good time on these meds. I’m eight weeks into my new bio drug Adalimumab. This morning I thought my ankles were not hurting quite so much, but they are back to being very painful. ☹️. I don’t know if you, or anyone else have just felt really ill on these meds. I have not felt so poorly on any meds as I do now. I just want to curl up on my bed and be left alone. Obviously I don’t do that, but by six pm, I’m done and need my bed. Hope you are all on one of your good days.🤗 x

[1608]

Hi I have Ankylosing spondylitis and was put on adilumimab 2 years ago and although they said my inflammation markers had gone down I didn’t feel much better. So I was taken off it. Then covid hit so I didn’t see anyone or was given an alternative. After another year of pain I had another MRI and was put on benepali 3 months ago. Although I feel slightly better I have structural Sacroillitis so feel that this is over shadowing the good that the TNF blockers are doing. I walk when I can do tai chi and try to keep active as much as my body will allow. Hope this helps