PEG skin prick test

[Rissa_L]

Hi everyone! I just got my skin prick test done at my allergist for PEG and Polysorbate, they all showed up negative but I refused to do part 2 of it which was several little shots in my arm to see if I react. Considering my anaphylactic reaction to the vaccine, I refused. Should I trust the Skin Prick Test alone? Because I am still struggling with this potential allergy. I do not know what I was allergic to in the vaccine. Also if anyone knows anywhere I can get a BAT testing (drawing blood) instead, to test for PEG please let me know! I am willing to travel anywhere in the East coast of America to the central America to get this done! I just want peace of mind and answers

[Debduck]

I've had a similar experience - I've had skin prick testing (twice) and intrademal testing for PEG and polysorbate and all were negative in the 30min time frame the allergist allowed. The macrogol 3350 and possibly the PEG2000 came up over the next few days and the bumps were elevated for quite some time. I showed no reactions to the vaccines on skin prick or intradermal testing and have had my first Astrozeneca jab without any reaction. I also had the BAT test (in Australia)as part of a trial testing the vaccines and that was negative too - the allergist mentioned something about CARPA- complement activated related pseudo allergy - I don't really understand what this means other than its not an Ig E mediated reaction - and you can still have nasty reactions with it. I've reacted to many medications / supplements with PEG in. I sympathise with your not knowing what you reacted to !!

[Rissa_L in reply to Debduck]

Wow intradermal is so scary. You are brave for going through with that, I’m so glad you’re okay! Do you know any reason why all those were negative yet you still react to products that contain PEG?

[Debduck in reply to Rissa_L]

Thanks. I think its the CARPA thing - my reaction isn't Ig E mediated. Good luck! Hope you get some answers soon!

[Rissa_L in reply to Debduck]

If I get a MAST cell testing done will that show anything that has to do with CARPA? And thank you!

[Debduck in reply to Rissa_L]

Really don't know - that would be a question for your specialist.

[Shiloh1]

Risa,

I work with a non profit developing a PEG antibody test to test blood samples to make it easier for people like you. If you, or others you know, are interesting in assisting in development, perhaps by contributing blood samples for testing, this might be helpful both to you and the non profit. Development is not anticipated to take long.

[Rissa_L in reply to Shiloh1]

I am interested! Please message me with more details or what’s your email?

[Shiloh1 in reply to Rissa_L]

My email is [e-mail]. The non profit is Children’s Health Defense. We are working with a lab to make available to the public a test for anti PEG antibodies. Please review their website. They are trying to do citizen science to help people like you and me. More importantly, they are trying to protect and defend the most vulnerable, our children.

[RobfromMichigan in reply to Shiloh1]

I just noticed your posting and would be willing to help. My email is [e-mail]

[River-daughter]

May I ask where you were able to get a skin prick test? I’ve been unable to find an allergist willing or able to do one. One allergist offered to do a Miralax skin test, but told me outright that it wouldn’t tell them much (she said it would just make them feel better, so I’m not sure what she meant by that).

[Rissa_L in reply to River-daughter]

Mine was actually a skin prick test that had miralax. Here’s what was tested. And yeah, I don’t know if I can trust the skin prick test alone. I don’t know what to do!

Peg/polysorbate spt

[River-daughter in reply to Rissa_L]

Thanks for sharing this! I’m really unsure what my allergist meant when she said it just “makes them feel better.” She did add that it didn’t tell them very much. I’m still looking for an allergist familiar with this allergy, so if I find out anything more specific I’ll definitely post it here.

[bestusedbyblue in reply to River-daughter]

I had a patch test done by my dermatologist for another allergy, about 15 years ago and propylene glycol showed as my 2nd strongest allergy. He knew all about it. Asked my tons of question about my skin and reactions to different things. Anyway, he proved to me that he knew what he was about. I still see him today. Since this is in so much foo, artificial flavor, color, scent, etc., I would have facial swelling, swelling in tongue and lips and mouth sores. I use children's Benadryl as adult Benadryl has propylene glycol it it. Any thing that causes facial swelling can also cause throat, tongue and bronchial tube swelling, so watch this reaction. My dermatologist also said to stay away from allergist as they like to give shots. I have had medication allergies for years and I don't get shots. A lot of times the glycols are not listed on the label as they are considered a secondary ingredient as a carrier for flavor , scent and color. So watch out for artificial on anything. If you want to find out about a drug, enter Label and the drug name. This will take you to the FDA, last page lists all the ingredients.

Since I have dealt with this for such a long time, I could go on forever. I will just give a few more helpful thing.

Eating out - salad no dressing, almost all meat is dyed.

Shopping - Dollar store, less expensive items, less ingredients and they will usually use glycerin, or something for a base.

Dyes - there are no safe dyes and most or made with PEG. I can not wear any color but white to sleep in, as I have major itch attacks with spreading welts.

Something you just have to give up. There is no alternative. If you are really bent on perfume, put in on you pants cuff. But you can still smell it, so be careful. I use essential oils.

Try a dermatologist and get a good old fashioned patch test. Mine made me sick, I had 108 patches and it really whacked my immune system, but I was ok in a few days. Research, research. A magnifying glass for reading labels and a list of the most common used names for this poison. I have a list , my kids and my husband.

I have a two page list of allergies. Don't let anyone, ever tell you allergies are not serious. They are, I have been in the hospital several times and it is scary. Eat natural, forget takeout and try as many natural personal care items as you can find. I even have bamboo socks as I am allergic to elastic. Take care.

[RobfromMichigan]

DebDuck, I am new to this site but can let you know my allergist was not very familiar with my request for a test for PEG. He did the test and started with a superdiluted amount to start as I had feared an event if I received too much. he started at 1/1000000 ratio. I manifested itching on the top of my mouth at 1/100000. He said i should not even have noticed that but we did continue the SPT (skin prick testing) at 1/10000 he introduced an intradermal dose (I think this is where you concerned). ALL reading I had seen were intradermal at 1:10 and ALL had severe reactions so I was very concerned not to start anywhere near there. At this point I did manifest a visual reaction (I could not see but informed him immediately upon that injection that I would show.) I did have a minor reaction managed with antihistamines. He immediately stopped all further testing. The only plan he could recommend was avoidance. I am seeking addition testing now with a leading Physician who will be testing with me He will be the side by side control subject to verify and confirm accuracy of the test. My triggering event was the Moderna Covid 19 Vaccine and had IMMEDIATE reaction before the needle was out of my arm. Hope this helps

[Rissa_L in reply to RobfromMichigan]

Wow I’m so sorry you had to go through that. That’s why I didn’t to intradermal testing. My reaction was to the Pfizer right after the needle was taken out. If u don’t mind me asking what further testing are you doing if you know you reacted to the intradermal? I’m trying to look for a blood or BAT for it but so far no luck

[JAG67]

I recently had the skin prick tests done. I was positive for PEG and negative for polysorbates. I showed a minor reaction to the polysorbates but not enough to be considered a positive. Seems strange because the bump on my arm still hasn’t gone away. The PEG testing was done on my back. They said I was definitely positive on that. I wish I would have had them take a picture. They said anaphylactic reactions would be very rare with this testing but I was where I needed to be if it did happen. I understand your nervousness because I have also made trips to the emergency room because of reactions. My insurance company is denying any of the compounded meds that I need because not every ingredient is FDA improved. They sure don’t care about that with the Covid vaccines ….which is the the reason I now have a PEG allergy. Every time I hear them push booster shots I want to scream. Good luck to everyone and I so appreciate learning from all of you. We are a minority group with a major issue.

[Lucy-Ella]

Hi DebduckWhat is a BAT test and who was the immunologist who saw you. They sound very thorough

Regards

[Debduck in reply to Lucy-Ella]

Sorry only saw this now- its a basophil Activation test or something like that. I had it at the Royal Adelaide hospital as part of a trial for the COVID vaccine.