PG vs PEG vs Polysorbate

[findtheanswernow]

PG vs PEG vs Polysorbate 80 - If you're allergic/sensitive to one, are you typically allergic to the others? Can anyone help clarify? My son was tested and confirmed allergic to PG. He was not tested for the other two. In fact, I've never heard about Polysorbate 80 until I was doing some reading today! (Apparently PEG and Polysorbate 80 are very similar?) Appreciate any clarification or wisdom others have to share - thanks.

[kerrykuzak]

If you want information about the other chemicals similar to the glycols, write me and I'll send you a paper I wrote. [e-mail]

[Jacquie7]

This is what our pharmacist said to my husband seeking advise on the vaccines.

"PEG is a small molecule and polysorbate 80 is a large molecule with what I will call "pieces" on the outside of the molecule that are identical to PEG. This is why there can be cross-sensitivity. In the past the cross-sensitivity didn't show up very often. Because these compounds are used in so many consumer products more people are producing antibodies to them and more allergic reactions are showing up.

I can't say for certain whether you would have this cross reaction or not, and we have not administered to anyone we know has a PEG allergy. There is a report of one woman with a PEG allergy who got the vaccine willingly and had fairly severe headache, chills and a high fever. Deep on the CDC website it advises that a consultation with an allergist-immunologist should be considered to determine if you can safely receive the vaccine.

My opinion is that if you decide to get it, it would probably be best if it was under the supervision of someone or in a place that can handle a severe reaction if it occurs."

All of his doctors have advise him not to get the vaccine. We can't even find a hospital that would administrate and supervise him.

Hope this helps,

Jacquie

[findtheanswernow in reply to Jacquie7]

Thanks Jacquie - helpful to hear an explanation in easy to understand terms! My question wasn't related to the vaccine (thinking more about food ingredients) but again, good to know. We definitely won't be getting the vaccine - I have sourced Ivermectin tablets that do not contain and PG, PEG, Polysorbate - from the data I'm reading I feel more confident in this route anyways. Also taking extra Vitamin D and Zinc supplements. Maybe an option for your husband to consider ... thanks again.

[River-daughter in reply to findtheanswernow]

If you are going this route I would exercise caution. Coronaviruses are relatively easy to kill and while many things, including Ivermectin, can destroy the Covid-19 virus in a Petri dish, all medications can be toxic in higher than recommended doses and multiple studies have reported they have not yet found a human-safe dosage of Ivermectin that is able to treat the virus in a clinically meaningful way. That said, there are other treatments outside of vaccines available.

While many medications are used for multiple maladies, the tablet size of Ivermectin that is usually prescribed for human use with parasites will contain a high dose meant to be taken roughly once a month on average, and high doses such as these are not intended or safe for the much more frequent dosing many people are administering with Covid-19. Especially for young people.

The safest thing to do would be to check with your son’s doctor and allergist on possible treatment options outside of vaccines, given his history. I hope this helps!

[2dog5]

I am allergic to PEG but fine with polysorbate 80So far

[River-daughter]

PG and PEG are similar but different enough that it seems like you can be allergic to one and not the other, although many people are allergic to both. It appears to be the same with PEG and polysorbate 80. I’m allergic to PEG (medically diagnosed, my first reaction was a giant torso rash), but I don’t seem to react at all to polysorbate 80 or PG. I want to qualify that statement by saying I have never had anaphylaxis even though I have had PEG exposures throughout the years that have made me quite sick; however, it might not be the same for everyone and if your son is anaphylactic to PG I would talk to an allergist about getting him tested for other, similar allergens.

It could depend on how you were sensitized, I guess. I was sensitized to PEG via a series of PEG asparagenase chemotherapy shots, which I suppose could possibly explain why only PEG, and not PG and polysorbate 80, affects me. It could also just vary from person to person. Maybe someone with more experience or training could weigh in here, as this is just my personal conjecture.

If you’re asking because of the vaccine booster, here’s my experience. The allergists I spoke to were only comfortable with me getting the Janssen vaccine (J&J) due to my history. I was told to pre-medicate with 24 hour Claritin (which is PEG free) in a specific way/dosage before my appointment, just in case I did react to the polysorbate 80, and I had no issues. I had my booster the same way. Both shots made me quite sick with headache, backache, etc., but I didn’t run a high fever like the woman the other poster mentioned (mine peaked at 101, and only lasted for a few hours). My other symptoms were all on the paperwork and lasted three days for me and then broke with no discernible allergic reaction.

I hope this helps in some way.