A few weeks ago I mentioned that I was trying this (1/2 teaspoon in morning tea) as I had heard it was useful at preventing dementia as well as improving mood. At the time others mentioned they had read that it can affect warfarin so I was careful to keep an eye on my INR readings even though my next offical one is not till Friday.
I thought some feed back might be helpful even though it seems still confusing.
After two weeks my INR had dropped from the usual 2.4 to 1.8 . I admit that at one stage during that second week I had missed all my evening drugs due to being out at a meeting. I therefore increased my warfarin from the usual 3.5mg to 4.5 for two days and 4mg therafter and tested again after two weeks. OOPS INR 4.3! I missed one nights completely and return to 3.5 daily resulting in the following_:- 27/9. 4.3. 30/9. 2.2 . 6/10 2.4 and we will see what happens on Friday.
So it does appear that lions mane may reduce the affect of warfarin but not as much as missing a dose!
As for any benefits, my wife says I am more cheerful (thats a lie) but just perhaps I may not be quite so forgetful where I put my reading glasses. Since I had a two for one Holland and Barrett deal I have stock for another six months at the present rate (Sam tried it but hates the taste) so one way or another we shall have some facts eventually.
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I love INR variations. I managed to stay at 2.5 +/- 0.2 in the run-up to my ablation, (in spite of stopping diltiazem which had put me up by 0.9! the week I went on it at 120 mg), by some judicious extra doses, based on my pre-Dilt weekly of 28 mg. But after my ablation, the figures were such that it looked like 26 mg was enough. Result next week, 1.9! Went to 28 mg /wk, next week result 2.1! Which was on the same day as restarting Diltiazem at 60 mg, just to throw a spanner in the works. So stayed on 28 mg, expecting the Diltiazem to put me up closer to 2.5, back next Monday. Slight trepidation as my warfarin is primarily for my mechanical aortic valve. 🤞🤞
Yes, only warfarin for mechanical valves, not sure about tissue or artificial tissue valves. Re BobD's comment, that sounds to have been a while ago. The modern mechanical AVs are designed to resist clotting better, (e.g. mine is an "open pivot" valve where the leaf pivots are 'washed' with blood), and have a target INR of 2.5 (2 to 3 range). There is talk of a valve with target INR below 2, but I wouldn't presently trust the ability to stay within the tight range necessary.
Thank you,don’t need replacement valve yet( bicuspid with mild stenosis ) but like to understand in advance. I remember my dad said he could hear the mechanical valve clicking like a clock. That would dement me! But if needed.. thank you x
That wa a bit of a dilemma as you didn’t really know if it was the missed dose or the Lion’s Mane that caused the fluctuation. Good that you have your own Coagu-check as that went a bit high 🥵. Hope it stabilises for you Bob and you get good results from the Lion and it’s a roaring success lol. Keep us updated please.
So it does appear that lions mane may reduce the affect of warfarin but not as much as missing a dose!
Thanks for your review. But you might want repeat the experiment, because the literature I read concludes the opposite.
It says that lions mane has an anticoagulating (thinning) effect on blood and therefore may be contraindicated for those on anticoagulants
Because you're on Warafin, you are able to make adjustments with dosage. But for those of us who are on the newer NOAC's we can't and probably should not take lions mane without consulting our doctor's or pharmacist, assuming they're familiar with it.
Warfarin is the orignal anticoagulant. First used in 1948, famously by Ike. (not Turner but can't spell Eisenhower). Do you mean how does it affect DOACS. ? No info on that one.
I stand corrected, apologies. That would have been the correct question.
I have been on xarelto now for about 10 years and have always thought the main difference between it and warfarin is one thins the blood and the other prevents coagulation. You live and learn.
None of them thin blood. This is a horrible missnoma we at AFA have been fighting for years though sheer weight of numbers seems to have overtaken us. It seems as Thomas suggests that doctors think we are too thick to understand which I for one find insulting.
Warfarin is an anticoagulant. It does not thin the blood, but delays coagulation. "Blood thinner" is an unfortunate name for anticoagulants. It is an unhelpful description widely used in the USA, and increasingly so in the UK. We are allowed to call an antibiotic an antibiotic, and a antihistamine as a antihistamine, but some medics think we are too thick / unintelligent to understand the word anticoagulant, so call it a name describing what it doesn't do.
It doesn't. It simply has anticoagulant (thinning) properties of its own. Think high dosages of garlic or fish oil.
So the issue is not how lions mane effects warafin or NOAC's, but rather is it a good idea to add an additional anti-coagulating supplement if you're already taking an anticoagulant such as warfarin or a NOAC.
From what I've read the answer is no. It's not a good idea. Now those taking warafin may work around this by reducing their dose. But those of us taking NOACs cannot do this, and therefore should be extremely cautious before taking lions mane or any other drug or supplement that has an anticoagulating (thinning) effect on the blood.
I have memories of a holiday with my daughter in Crete. She moaned about going to Heraklion in the heat!Good holiday though. Think we stayed in Agios Nicholaos.
Youre doing so well you could contemplate another trip when its not too hot.
Just googled Wanda Ventham & yes you are showing your age cos she’s 89 now! Had quite forgotten she is Benedict Cumberbatch’s mum! So - “Thanks for the Memory”…..🎶
I've been to Crete lots too in the past Rainfern. We started off in Hersonissos and then moved south and visited Plakias many times sometimes twice a year. Not been back for many years now and I guess I'd be shocked at how built up and commercialised these places are today.
It’s lovely to still dream of those places. We went to Loutro and Souja in the south, Ellos in the mountains and Hania. My husband just dropped it that he’s not up to the journey there with his chronic fatigue. Well sod that. Fancy a trip to Crete Jean? 😂
Too bad you can’t do cannabis tea. In NM we can grow our own for personal use. Decarboxylated in the oven at 250(120C) and adding a quarter teaspoon to a cup of PG Tips makes all anxiety (which can contribute to arrhythmias) go away. Not so good regarding short-term memory or motivation to work however! Ha!
does it come in a capsule I’m a really sensitive to lousy taste lol do you feel more focused? I am on Xarelto. I wonder if it goes for all anticoagulant
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