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Changing from Adoxaban to Apixaban … what to expect?

Rainfern profile image
15 Replies

Good morning forum. While waiting for a second cardioversion the medics have decided to change my anticoagulant from Adoxaban to Apixaban (the low dose Adoxaban I was on until this morning could be a bit borderline if I put on just a pound or two weight). A bit fed up as this delays the cardioversion for a few weeks.

So I’m just wondering if there’s anything I should know about Apixaban and the difference between this and Adoxaban in peoples experience. I believe they work in pretty much the same way, so I doubt there’s a lot of difference, but it would still be good to know in advance what to expect.

Thank you, Jo

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Rainfern
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15 Replies
BobD profile image
BobDVolunteer

Edoxaban is the newest of the DOACs and is being widely used due to supposedly being cheaper. Apixaban is generally considered by most doctors to be the safest of the bunch.

Sorry but I do not understand what you mean by marginal if you put on weight? DOACS have no testing like warfarin.

Rainfern profile image
Rainfern in reply toBobD

Edoxaban dose is linked to body weight more than other factors. I would have to double the dose if I put on just a couple of pounds, and they don’t trust me to stay within my limits! Too much strawberries and cream around this time of year I guess.

SuziElley profile image
SuziElley in reply toRainfern

Really? 😳

Rainfern profile image
Rainfern in reply toSuziElley

That’s what EP and cardio nurse tell me … though obviously age and fitness etc must be taken into account.

Barb1 profile image
Barb1 in reply toRainfern

I have been on Edoxaban since it came out and weight has never been mentioned, even when I put on nearly a stone of fluid (later removed in hospital.)

meadfoot profile image
meadfoot

I was to be switched to edoxaban, the lower dose as I am of slight build. I read that it was good regarding lower chance of bleeding but the lower dose was not as good on the stroke prevention front. After a visit with my GP last week I am not changing to edoxaban.

Rainfern profile image
Rainfern in reply tomeadfoot

Thank you that helps to clear things up for me.

Silvasava profile image
Silvasava

After a bout of flu in January that nearly finished me off I lost so much weight my dose of Edoxaban was lowered. My pharmacist has said I need to be over 60kg to go back up. I've been on Edoxaban since a stroke in December 2019, no issues with the drug whatever. HTH

2learn profile image
2learn

Hi, I found when switched from warfarin to apixaban my arthritis got much worse. muscle ache is a side effect.

Rainfern profile image
Rainfern in reply to2learn

unfortunately Adoxaban can also cause joint problems … sorry to hear you’ve had a nasty side effect

RoyMacDonald profile image
RoyMacDonald

Never had any issues with Apixaban.

All the best.

Roy MacDonald

Uniform96 profile image
Uniform96

Hello, I have been on apixaban for five years and no problems.

wilsond profile image
wilsond

Apixaban the first choice of my EP Proff Osman. I'm staying on it forever! Absolutely fine since 2017

Afibflipper profile image
Afibflipper

I’ve been on this one for over 12 months, suits me fine. Good luck with the 2nd CV

Rainfern profile image
Rainfern in reply toAfibflipper

Thank you, that’s good to hear 😀

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