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Direct oral anticoagulants as safe, e... - Atrial Fibrillati...
Direct oral anticoagulants as safe, effective as warfarin

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seasider18
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I haven’t seen any evidence, but my suspicion is that DOACs are safer then Warfarin, but less effective. The studies I have seen have compared DOACs with Warfarin where INR is in range less than 60% of the time, whereas it is relatively easy to achieve over 90% with self monitoring and self dosing.
Does warfarin offer a higher degree of stroke protection? I would think so because you have a monitoring system in place unlike the newer drugs.
For me one DOAC wasn't as safe as Warfarin, and rather than be "bitten" a second time by taking a different DOAC I reverted to Warfarin. The lack of safety was not in relation to anti-coagulation but to a very rare side effect.
What was the rare side effect ?
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