NAC: Treating Apnea that contributed to AFIB

[noviceAFIB]

After trying 0, 1/4, 1/2, and 1 teaspoonful of NAC (n-acetyl-l-cysteine powder) at bedtime, my AHI (pulse oximeter adjusted index) has dropped significantly.

It is tart to me so I mix it with warm honey water.

Tolerance of NAC & impact on AHI probably will vary greatly depending on individuals; only way to find out is to try it; just **beware** that NAC does THIN your blood; I wait over 3 hours after my 5mg of Eliquis before taking NAC.

Self-hacked site has nice summary on NAC benefits.

Next experiment is adding glycine to see if it helps or not (glycine is needed in Glutathione synthesis).

[Hidden]

What is the view of your consultant regarding what you are taking?

[noviceAFIB in reply to Hidden]

As for consultant's view, not sure; however (a) specialists around here they are not the best & (b) too recent of a development & (c) my bodily empirical response speaks the loudest & (d) risk of drug interactions are minimized by slow gradual increase in dosage after Google/Youtube searches; you are rightfully cautious, please do consult with whomever you trust before trying NAC if you do indeed have apnea; just sharing what works for me specifically.

[Hidden in reply to noviceAFIB]

Yes I have sleep apnoea, diagnosed 7 years ago, interesting info.

[Hidden]

I'm sorry but I've no idea what this is so can't make a helpful reply!

[KathFrances]

I take NAC and L-glycine every night before bed. I think it helps sleep - not sure whether it affects my AF or not. No NHS practitioner I’ve met has heard of these sorts of supplements, but I do a lot of online research before I try things and go slowly to check out any effects.

[noviceAFIB in reply to KathFrances]

#1

May I ask what is your proportions of NAC relative to Glycine (like 2mg NAC per 1mg of Glycine)? My Glycine will be arriving this coming Friday.

#2

How do you measure the impact/effects?

In my case, I use SPO2 assistance with pulse oximeter nightly.

I noticed my O2 level flattens above 95 for over 3.5 hours duration with NAC.

Before NAC, apnea events occurs after ~2 to 2.5 hours.

[KathFrances in reply to noviceAFIB]

The ratio of NAC to L-glycine that I’ve found most commonly recommended is 1:4. For example 50mg NAC to 200mg glycine. I take this, or sometimes up my dose of NAC a bit. I’ve been treating various auto-immune and other conditions for 30 years, both by myself and with a functional doctor, so I use a combination of research, medical professional input, intuition and self-observation.

[noviceAFIB in reply to KathFrances]

very helpful; thanks for the info