I am suffering from AF last 3 years, I am asymptomatic, I am prescribed Ramipril and Bisoprolol and also take Xarelto the anticoagulant. Can anyone let me know if either Ramipril or Bisoprolol affects the heart rate (pulse), or do both have nought to do with that area... Reason I ask is I noted that after some days while on the high seas for various reasons did not take either tablet (for 7 days) except Xarelto , I noted my blood pressure each day was as good as it is when taking the tablets during those 7 days, although heart rate was just under 100 each day. I therefore am wondering which area each tablet moderates .i.e. rhythm , heart rate, etc,- as it seems to me my main concern is the heart rate rather than blood pressure. I am booked to see my GP and will ask this question, but maybe I can get some information from those reading this who are familiar with these drugs what exactly each is tackling. I wish to offer those who respond my thanks in advance.