AF Association
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I had a heart attack 4 years ago - from my very stressful job- and it was not properly diagnosed so when I eventually got help there was serious permanent damage. I understood the blood test called ProBNP showed results that indicated heart muscle damage (5500 was the score). In subsequent years the level tested by ProBNP stabilised at 700 and was not a reason for concern when I had my annual check ups. A year ago it suddenly soared to 2300 (after a year of a lot of personal stress I must say) and my cardiologist performed angiogram and TEE but there was no other identifiable deterioration. The original heart muscle damage means there is mitral regurgitation and AF and surgical valve repair could lie ahead but damage is still "moderate" - not bad enough yet. The only explanation I have been given for the increase in my ProBNBP score is ongoing permanent AF. Does anyone else have experience with this? My 6 month checkup is next Monday. I am in South Africa. I am fit and well, daily 1 hour exercise like water aerobics or line dancing and do it with ease. Lost weight and cholestrol is not - never was- the problem but I do take a statin as well as warfarin, bilocor, furosemid, potassium chloride. I am 66 and retired.

7 Replies

Although you have AF, annemk, I suspect this post might be better placed on a different forum.

Has anyone any suggestions?


I would be happy to follow up suggestions.


British heart foundation still on HU think sometimes their nurses advise

1 like

Goldie11 would be able to comment if he sees this


Are the units pg/ml? If so these levels are very high and if due to heart failure alone, I am surprised that you can do so much exercise. Well done!

A better assessment for heart failure is the left ventricular ejection fraction, which I take it you should know as you know about valve functions. The BNP does increase with AF and also age andsome other conditions (pulm hypertension and COPD).

Have you had your ejection fraction measured and other heart failure assessments done on ECHO? as well as other causes investigated?

If so there is probably no point in getting too worried if you are functioning well!

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Thank you. I will get back to the reports and check on other assessments that were done. Your input is really helpful.


From annemk

I see in the report

"global hypokinesia with and ejection fraction of 45% with normal pulmonary arteries""Normal coronary arteries" Blood Pressure 120/80 pulse 83 beats (at home its usually 60 beats) Saturation 96%. No Oedema. Peripheral pulses palpable. "

"resting Electrocardiogram Atrial fibrillation heart rate 97. QRS 94. QRS Axis 42. T-wave 22. Poor R-wave progression. small Q-waves in the inferior leads probably related to previous MI. "

"Exercise Electrocardiogram - patient attained a heart rate of 63 beat/min with non-significant ST/T-wave changes."

"Echocardiogram. Aorta 3.1 Mild AR Vena contractor .7. MR EROA .06. Right ventricle regurgitant volume 7.9 fraction 14.2. Eccentric jet along anterior wall. Left Ventriculr internal diameter 5.3 left ventricular internal diameter in systole 3.7 ejection fraction 57% pulmonary artery pressure 40mmHg"

Last year the big question was should I have a mitral valve repair and the final decision was no.

I have BMI 26, no pain, up and down stairs all day, usually sleep very well.

Thanks for any input.


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