I had a heart attack 4 years ago - from my very stressful job- and it was not properly diagnosed so when I eventually got help there was serious permanent damage. I understood the blood test called ProBNP showed results that indicated heart muscle damage (5500 was the score). In subsequent years the level tested by ProBNP stabilised at 700 and was not a reason for concern when I had my annual check ups. A year ago it suddenly soared to 2300 (after a year of a lot of personal stress I must say) and my cardiologist performed angiogram and TEE but there was no other identifiable deterioration. The original heart muscle damage means there is mitral regurgitation and AF and surgical valve repair could lie ahead but damage is still "moderate" - not bad enough yet. The only explanation I have been given for the increase in my ProBNBP score is ongoing permanent AF. Does anyone else have experience with this? My 6 month checkup is next Monday. I am in South Africa. I am fit and well, daily 1 hour exercise like water aerobics or line dancing and do it with ease. Lost weight and cholestrol is not - never was- the problem but I do take a statin as well as warfarin, bilocor, furosemid, potassium chloride. I am 66 and retired.