I have PAF but also have a slightly enlarged prostate and have been taking Tamsulosin for nearly 10 years which coincidentaly is how long I have had PAF. By Googling in "Can Tamsulosin trigger AF?" there are sites which say that it can. Also the information leaflet that comes with the packs of Tamsulosin say that one of the side effects can be "Irregular heartbeat". Although I have disclosed to the various Cardiologists and EP's that I am on Tamsulosin none of them has mentioned that this may be the cause of my PAF. Any thoughts much appreciated.