Dad’s routine urine report showed “ trace protein “. He has never had this show up earlier ?
What has been added in the last couple of months is
1)Whey protein shake - appx 40 gms a day. ( he is 70 kg )
2) Metformin 1750 mg a day
3) Xtandi - 120 mg a day
4 ) Orgovyx - 120 mg a day
He is low diabetic - Fasting sugar around 120 mg but post prandial ia within limits and hba1c 6.7
Wondering if anyone has had trace protein in urine show up.
Doc has said to do a protein/creatinine blood test to quantify the protein and if it’s low he says to ignore it and to continue with the high protein diet.
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Trace amounts of protein in the urine, also known as proteinuria, can occur for a variety of reasons, and it may not always indicate a serious problem, especially if it's just a trace. However, it is worth looking into whether the recent changes in your father's medications or diet could have contributed. Let's break it down:
1. Whey Protein Shake: Increased protein intake, especially through supplements like whey protein, can sometimes cause proteinuria, particularly in individuals who have underlying kidney conditions or are consuming more protein than their kidneys can efficiently process. For a 70 kg individual, 40 grams of protein from whey shakes may not be excessive, but this varies based on overall dietary intake and kidney function.
2. Metformin: Metformin is generally not known to cause proteinuria. However, in individuals with existing kidney issues, it can affect kidney function and may indirectly influence urinary protein levels. Kidney function tests (e.g., creatinine or eGFR) would help in assessing this.
3. Xtandi (Enzalutamide): Xtandi is not commonly associated with proteinuria, but it has been reported to cause kidney-related side effects in some cases. Monitoring kidney function is recommended while on Xtandi, especially in those on long-term therapy.
4. Orgovyx (Relugolix): Orgovyx is a GnRH receptor antagonist used in prostate cancer treatment and doesn't have a direct known link to proteinuria. However, any systemic therapy can place stress on various organs, including the kidneys.
Your father's doctor is right in recommending a protein/creatinine ratio test to quantify the protein in the urine and assess if further evaluation is needed. If the protein levels are low, and kidney function tests are normal, this might not be a significant concern. Nonetheless, ongoing monitoring, especially with the added protein intake and medications, is wise to ensure his kidneys are functioning properly.
Do you have ChatGPT application for iPhone? My friend is asking.
Yes, the ChatGPT app is available for iPhone. Your friend can download it from the Apple App Store. It's compatible with iOS devices and provides the same features as the Android version.
Double check what ChatGPT prints because I have often caught it fabricating replies. It is excelent as a starting point, but when diving deeper it may present made up data/sources/links etc. Always ask for the link to the original source of information and double check it exists and it isn't fictitious (it has hapened to me).
My retired engineer's take: Kidneys clean up the blood from proteins. If the protein content in blood isn't abnornal, so that it clogs the kidney filtering function, then the latter are not functioning as expected. Possible causes:
"... In addition, ADT can increase the risk of kidney injury due to metabolic alterations and by lowering testosterone to castration levels, antagonizing the vasodilating effects of testosterone on renal vessels [16,17]. Several studies described a potential kidney injury during bicalutamide treatment..."
It is a very bad idea to stress the kidneys. Compared to other organs they are very prone to damage (that is one reason of us having two where in comparison one liver, one bladder, etc.) According to my urologist bladder is the most forgiving organ in the urinary system.
I totally agree with you and thanks for the contribution it is great! But hopefully he will be fine if he distribute his protein intake during the day in multiple small portions? That could hopefully be helpful. And avoid dehydration. Drink water and not alcohol.
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