My MO has asked my opinion on resuming Xgeva after stopping for an ONJ scare -- it wasn't ONJ, just some TMJ issue.
I have not been able to find the post where you linked to the two trails you mentioned above. f.y.i. I am post ADT, chemo and Pluvicto with DEXA scores well above +1 for both hips (mild osteopenia in spine) -- MO wants Xgeva every 3 months as he believes it is SOC.
Would you please repost the links so that I can share with my MO? As you know, quoting some guy, no matter how respected, from the internet means nothing to a doctor.
I take 120 mg every three months, since Jan 2020. I took a year of in 2022-23 to do some dental work. The "correct" dosage seems to be the individual doctor's opinion.
I was taking the 120 every 3 months. Many MO's have learned that monthly injections had little benefit over the 3 month, and a higher incidence of side effects.
My 2 ¢: In my case my retiring MO said I didn't need Xgeva (high strength monthly or quarterly shots) or Prolia (low strength 6 month shots) but my new one said I did need Xgeva.
So I did a consult with an MO at Memorial Sloan Kettering in New York City and she said she felt it had a therapeutic effect beyond strengthening bones. So I am back on it -- well on hold until a dental issue is resolved.
My most recent DEXA showed very strong hips and only mild osteopenia in my lower back, so there is no need for Xgeva for my bone strength.
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