Dr Sartor and dr Karmann discuss lead... - Advanced Prostate...

Advanced Prostate Cancer

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Dr Sartor and dr Karmann discuss lead 212 radioligand and why dr Karmann thinks it is better than lutetium and actinium

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in a nutshell, alpha emitter (more powerful than beta), shorter half life (could be synergistic with immune system and allow for more frequent dosing)…they are not talking directly about prostate cancer but I suppose prostate will be a candidate for trials!

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Maxone73
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Garbonzeaux profile image
Garbonzeaux

The good doctors dance around the "short" half life of Pb212, but never say what it is (10.64 hrs). As it turns out, the lead itself is a beta emitter, but it decays to bismuth212, which is actually the alpha emitter, with a half life of about an hour. Technical detail of no particular relevance, I guess.

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