Second Gen ADT Drug Issues

[Teufelshunde]

Dont remember seeing this on here yet. I guess one weighs increased risk of dementia vs stopping PC. Wouldnt want to be in that position. I remember back before my SRT went on Bicalutamide for one month before SRT started and then stopped when I read that is also linked to dementia. Crap.

urologytimes.com/view/analy...

[Tall_Allen]

It doesn't say "dementia," it says "cognitive toxic effects." Such effects can include trouble concentrating. Most such effects are low grade. Even so, incidence is low.

"Across 4 studies with a combined enrollment of 5267 patients, cognitive toxicities of any grade affected 2% to 8% of patients in the antiandrogen groups and 2% to 3% of those in the control groups."

[SteveTheJ in reply to Tall_Allen]

True. I have trouble concentrating but it's far from "toxic". Keep going, don't look back.

[Magnus1964]

Everyone responds differently to ADT drugs. I was on 3 different drugs fore decades. I don't think it impaired my mind.

[Schwah in reply to Magnus1964]

I don’t remember if it I’m paired my memory. Lol

I couldn’t resist

Schwah.

[pakb]

My grandfather was on lupron from 1988 to 2009. He did the NYT crossword puzzle each day in pen, golfed, ran his community board- was sharp as a tack until he passed in 2010. Everyone's body reacts differently to treatments and in many cases, benefits far outweigh risks.

[dhccpa in reply to pakb]

That's encouraging to an almost 5-year Lupron user.

[pakb in reply to dhccpa]

My husband has been on lupron for 6 years next month- it keeps me hopeful as well! My grandfather had the smoothest legs from treatment and he loved to joke about it.😂

[dhccpa in reply to pakb]

Yes it definitely diminishes the need for cutting and trimming!

[fireandice123]

If I have any mental decline while on ADT I think it’s more likely caused by the fatigue I feel. At times it’s hard to concentrate when tired.

[j-o-h-n]

Been on Lupron I think 15 years....definitely not 51 years.........

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 07/09/2023 5:48 PM DST

[Teufelshunde]

I see lot of posts about being on ADT for years and years. Again, the article is about the next gen ADT, so if you are using the ones the articles talk about, I would be interested to hear your experience. Yes it is a simple choice on lesser of two evils, as is common in PC journey.