Prazosin

[Scout4answers]

Any one else buying it from India?

[cesanon]

What's so good about it?

[Scout4answers]

renalandurologynews.com/hom...

It was used as a treatment for LUTS in this study not for High Blood Pressure

In that study, 147 men received prazosin, a quinazoline alpha-blocker and 72 received tamsulosin, a non-quinazoline alpha-blocker, to treat LUTS. Another 84 men naïve to treatment with alpha-blockers served as controls.

[tango65]

This is the link to the full article:

ncbi.nlm.nih.gov/pmc/articl...

[BruceSF]

I get mine through Medicare part D, I get 90 pills for $15 or so. I have been recurrence free since I stopped Lupron + Abiraterone in January 2020, so I I think it's likely to help prevent recurrence in high risk cases.

[Scout4answers]

I certainly hope you are correct. following you closely Bruce

[StephH72]

interesting. I read the study and it does seem promising. What dosage are you taking? The study said 1-2mg of prazosin was most helpful, is that correct?

[Scout4answers in reply to StephH72]

I am taking 2mg in morning and 2 mg at night.. I think the study had higher doses if my recollection is correct... (often not these days) ;-))

[gsun in reply to Scout4answers]

Yes because of the short half life of it.

[Purple-Bike in reply to StephH72]

It was a retrospective study with 1-2 mg being used against LUTS. In an ongoing prospective study a higher dose is used. My take is at least 2 mg, perhaps 4 mg as Scout4answers is taking.Retrospective studies usually have severe limitations but for me an 83 % recurrence free survival rate for PCa patients after 10 years for prazosin users, vs 27 % for controls and zero % for users of another drug against LUTS, tamsulosin, P<0.0001, is intriguing.

[RCOG2000]

i get enzalutemide from India

[gsun]

I like this : In this study, prazosin showed superior inhibitory effect on proliferation in human androgen-dependent and androgen-independent prostate cancer cells.

This shows it can treat both cell types.

[gsun]

Where are you buying it in India?