Added to profile: My saga continues and... - Advanced Prostate...

Advanced Prostate Cancer

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My saga continues and has become more complex. I just added to my profile.

I am undergoing Docetaxol treatment while awaiting Lutetium 177 PSMA treatment. Small cell cancer seems quiet while adenocarcinoma is active. Always a balancing act with two cell lines.

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DenDoc
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Tall_Allen

The requirement of docetaxel before Pluvicto is only that you've tried it. If it doesn't work for you and side effects are too cumbersome, you have good reason to stop and you don't have to keep taking it.

Are you still getting FDG scans? I am concerned about your mixed cancers and that eliminating only the PSMA-avid cells, will give the other more room to take over:

prostatecancer.news/2019/12...

Take a look at the BiTE trials listed in that article. Because of "antigen spreading" they may not have the same concerns.

Have you had an IHC stain for DLL-3? If it's positive, you may be a good candidate for the DLL-3 trial:

prostatecancer.news/2016/12...

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