Article on updates for PC Biochemica... - Advanced Prostate...

Advanced Prostate Cancer

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Article on updates for PC Biochemical Recurrence.

JPnSD profile image
9 Replies

Biochemical recurrence develops in almost one-third of men with PC who have had local therapies.

an article on best approaches and updates discusses intermittent ADT

ascopubs.org/doi/full/10.12...

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JPnSD
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9 Replies
Tall_Allen profile image
Tall_Allen

I wonder where they came up with that incorrect statistic? Perhaps it's true if they don't restrict the time period to contemporary patients.

Scout4answers profile image
Scout4answers in reply toTall_Allen

Are you suggesting it is higher that 1/3 or lower?

Tall_Allen profile image
Tall_Allen in reply toScout4answers

Much lower in contemporary patients.

JRPnSD profile image
JRPnSD in reply toTall_Allen

Who collects those records? I had Biochemical Recurrence and I am sure it never got reported to any type of tracking agency.

Tall_Allen profile image
Tall_Allen in reply toJRPnSD

Why are you sure? Most institutions collect those data. With patient electronic records, they are usually de-identified and reported in databases like NCDB, SEER and various registries. They are required to collect and report on clinical trials.

JRPnSD profile image
JRPnSD in reply toTall_Allen

I received SOC, so no clinical trials were involved. My impression is that there was no tracking of the outcome given conversations with my URO.

maley2711 profile image
maley2711 in reply toTall_Allen

Could this explain the difference in numbers ......

urotoday.com/conference-hig...

" Following radical prostatectomy, approximately 27-53% of patients will experience BCR.1 However, only 30% of patients experiencing BCR after primary surgery will develop clinical recurrence, with only 16.4% dying from their disease. The main unfavorable prognostic factors are:

PSA doubling time (PSADT) of <=1 year

A pathological Gleason score 8-10.1

Tall_Allen profile image
Tall_Allen in reply tomaley2711

No, the problem is the dates.

maley2711 profile image
maley2711 in reply toTall_Allen

where can we look for the current more accurate numbers???

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