SHBG #s and free T : Testosterone... - Advanced Prostate...

Advanced Prostate Cancer

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SHBG #s and free T

Scout4answers profile image
13 Replies

Testosterone, Free, Calc<1 pg/mL

47 - 244 pg/mL

Percent Free Testosterone<0.9 %

1.6 - 2.9 %

Testosterone, Adult, Male<3 ng/dL

300 - 720 ng/dL

Testosterone, Bioavailable<1 ng/dL

131 - 682 ng/dL

.Sex Hormone Binding Globulin86 nmol/L

19 - 76 nmol/L

Can someone please help me interpret the SHBG #s, the T numbers look to be totally suppressed.

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Scout4answers
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13 Replies

T is suppressed. SHBG binds/transports tT. Your SHBG doesn't matter much when your tT is suppressed. 86 isn't very high - mine was about 300 prior to ADT/SPT/BAT. Every therapy has dropped it. It's sitting around 20-40 today.

But I guess the higher the better for SHBG since it should reduce your active T. Your numbers are so low it's probably a don't care.

Refresh my memory: are you on Lupron? Are you using any other anti-androgens?

Scout4answers profile image
Scout4answers in reply to

Lupron 250, days Zytiga 180 days, took 14 days off Z because of high liver enzymes. restarted Z @250mg today.

in reply to Scout4answers

That's right. Too early in the morning for me.

With the lower dose of Zytiga it will be good to test T again after a month or so (it was hard to track this down but T starts to recover after a month or so off of Zytiga - I don't know the variability of this). And of course Lupron alone will reduce tT but is it rare that it suppresses it to these levels.

Justfor_ profile image
Justfor_

They are with all the medication that you are taking.

"Calc" stands for "calculated".

There is this online calculator.

For Albumin they probably used the ballpark 4.3 if there was no specific measurement.

My Albumin varies between 4.36 and 4.70.

When not specifically measured, I use the median 4.55.

Free T calculator
Tall_Allen profile image
Tall_Allen

You are getting a lot of useless, anxiety provoking information. Why are you doing this to yourself?

Scout4answers profile image
Scout4answers

No anxiety, just trying to get as much info as I can, they may be meaningless now but when I go off ADTs they may give me a heads up as to how I am responding.

Tall_Allen profile image
Tall_Allen in reply to Scout4answers

There is a difference between data and information. You are just collecting useless numbers that cannot conceivably have any effect on treatment decisions. THe ONLY reason to have a test is because it can effect a treatment decision.

MateoBeach profile image
MateoBeach

Yes, Scout. You are on ADT. The whole purpose of which is to suppress testosterone to castrate levels, defined as <20 ng/dL of total testosterone. You are way below that so it is working. The rest do not matter when it is that low. Only if and when you come off of ADT and testosterone production recovers (or not) will the other numbers matter, even though it is true that free T is what is active.) you need not be concerned with it now because you are indeed castrate biochemically.

Scout4answers profile image
Scout4answers in reply to MateoBeach

Understood Paul

How are you doing with the J? any repercussions or side effects? Hope you are having a great vacation in Sydney instead.

Teufelshunde profile image
Teufelshunde

What dosage of Stinging Nettle Root and Avina Sativa gets these results best?

MateoBeach profile image
MateoBeach

It’s going well. Just a bit of fatigue from the radiation working inside. Sydney is lovely and exciting but intense and busy. Walking everywhere as well as ferries and fine dinners. Spending time with Marnie and Ron of APC and their family. That is the real treat.

Scout4answers profile image
Scout4answers

glad it is going well

Teufelshunde profile image
Teufelshunde

Yes, doing Free T tests (last 20.3). Total T 242. Taking the Avena Sativa and Stinging Nettle you mention currently. I think I will double until next blood test. SHBG is 65, at the high end of range. Currently taking Boron 9mg and Magnesium 400mg, so may need to up that?

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