TA's website has some BAT info. Does ... - Advanced Prostate...

Advanced Prostate Cancer

21,056 members26,262 posts

TA's website has some BAT info. Does anyone know of any data connecting BAT and radiation? The nearest one I found is a John's Hopkins study

8 Replies

prostatecancer.news/search/...

Johns Hopkins study isn't estimated to complete until 2027 and is of BAT and Radium -223. This isn't precisely what I was looking for... clinicaltrials.gov/ct2/show...

8 Replies
Fiddler2004 profile image
Fiddler2004

Thanks for sharing 💯

cesces profile image
cesces

BAT is pretty far out there on it's own.

It's purpose is to resensitize prostate cancer to androgen deprivation therapy.

BATs place is for use in the later stages of the disease.

Radiation's place is in the early stage of the disease before it has metastasized.

So this doesn't seem like it should be an issue of relevance. No?

in reply to cesces

I would have agreed but I ran across a couple of papers about using high testosterone, along with radiation, to amplify DSBs.

Scout4answers profile image
Scout4answers in reply to cesces

I am hoping to use BAT in the early stages to keep my self in a hormone sensitive state.

in reply to Scout4answers

Me too. Resensitization to AR drugs, delay of CRPC, and perhaps delay of resistance to other AR drugs are the things I hope for. Doesn't hurt that modified BAT is great for muscle and QoL. My friends ask me how I'm making the mass gains at 60 and I always tell them "get prostate cancer". My MO seems amazed at my state and always asks me about my programs. She has advice about some things but rarely tries to talk me out of anything I'm doing.

Scout4answers profile image
Scout4answers

Speaking of muscles, I have changed my free weight exercise routine to emphasize hypertrophy vs. strength - i.e. less weight, more reps and eventually more sets with much shorter rest periods in between. I used to do one set of ten exercises with 15 reps then repeat the list a second time.

Now I do the same lift with 15 reps, 3 times(sets) in a row with a very short rest in between, goal is to increase reps and sets until I reach muscle fatigue, then move on to next exercise.

I like your theory that PCa and muscles are competing for the same resources, so building muscles starves the cancer cells and inhibits their growth. Even if your wrong the result will be larger muscles ;-))

in reply to Scout4answers

I need to expand that section. Lots of theories and data.

But, yeah, doesn't really matter. Bigger muscles are better for me! :)

I'm currently doing two workouts a day. A 40-minute session in the morning that focuses on strength and longer rests (lots of simple 5x5s). A 15-20 minute hypertrophy session in the evening. It's similar to what you are doing, 8-12 reps and 30-60 second rests. Slow strict reps.

I've been doing this for a few months. Sometimes I go away from it for a week or so and then right back. Works great for me.

j-o-h-n profile image
j-o-h-n in reply to Scout4answers

Funny you mentioned reps...... my wife is my representative when she does exercise for me....... she's soooooooooooooo nice.

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 01/26/2022 3:46 PM EST

You may also like...

Batman BAT study updated

long-term results of those who have used BAT....

What Are Reasons Not to Use Bipolar Androgen Therapy (BAT)?

else here other than poshea tried Bat, or considered trying it? What are your thoughts about it?...

In whom does BAT work? Some new clues

always been, and still is, what are the biomarkers that determine if BAT helps, hurts, or does...

BAT: Bipolar Androgen Therapy: A Paradoxical Approach for the Treatment of CRPC.

near-castrate concentrations. Initial studies demonstrated that BAT is safe and produces clinical...

Bipolar Androgen Therapy (BAT) update (with olaparib)

great interest in the BAT trials. This one combined a PARP inhibitor, olaparib, with BAT. Here are...