BAT may re-sensitize PCa cells to hormonal therapies

[curious-mind1]

Using BAT before hormonal therapy agents may re-sensitize the cancer cells to next-generation hormonal therapies (among other benefits):

practiceupdate.com/expertop...

Happy holidays everyone!

Art

[Spyder54]

Yes! BAT before Enzalutamide seems key from this TRANSFORMER Study.Merry Christmas Art,

Mike

[kaptank]

Yes. BAT then enza looks a no-brainer. But abi does not respond so well (previous reports suggest) . It seems it works best with the lutamides

[Skipper238]

Thanks. I saw this article, too, after following your link. This seems quite hopeful. Merry Christmas to all. practiceupdate.com/content/...

[jfoesq]

Always nice to some promising new info.

[j-o-h-n]

Good Luck, Good Health and Good Humor.

j-o-h-n Saturday 12/25/2021 7:29 PM EST - Happy Christ's Birthday.

[MateoBeach]

Likewise am curious. I was on bicalutamide as alternative to ADT for nearly 5 years before it started “feeding” rather than blocking the AR and PSA began rising. This phenomenon is well recognized. PSA drops when bicalutamide is stopped. Since I am now on cyclic modified BAT (4 month cycles - 3 on SPT and 1 month off currently), I am curious if this might resesensitize me to bicalutamide in the off cycles again? Thanks for your post.

[GP24 in reply to MateoBeach]

Please update your profile, it does not mention the BAT therapy yet.

Good idea to start with Degarelix before using patches.