Landmark studies have re-ignited interest in the use of monitored single-episode high dose psilocybin for depression, anxiety and fear of death in cancer patients. Also being studied for PTSD and other indications. The following study referenced was a landmark one for advanced cancer patients.
My state of Oregon approved a legal program of psilocybin assisted therapy in Nov 2020 and is on a two year trajectory to rolling out the program with trained authorized therapists. (I have volunteered to be on the Oregon Psilocybin Program Board.) Yes I advocate for this and have experienced in Canada.
ncbi.nlm.nih.gov/pmc/articl...
"Conclusion: When administered under psychologically supportive, double-blind conditions, a single dose of psilocybin produced substantial and enduring decreases in depressed mood and anxiety along with increases in quality of life and decreases in death anxiety in patients with a life-threatening cancer diagnosis. Ratings by patients themselves, clinicians, and community observers suggested these effects endured at least 6 months. The overall rate of clinical response at 6 months on clinician-rated depression and anxiety was 78% and 83%, respectively. A multisite study in a larger and more diverse patient population should be conducted to establish the generality and safety of psilocybin treatment of psychological distress associated with life-threatening cancer."