PSMA-targered poisoning

[TheTopBanana]

hopkinsmedicine.org/brady-u...

Anyone know anything more about this? Sounds promising!

[6357axbz]

Yes it does. I’ve been really impressed with Johns Hopkins in combating metastatic PCa

[Hope59]

This sound amazing! Thank you, Top Banana! Go to bed! You are a wonderful daughter (and researcher!).

[Tall_Allen]

Many PSMA-targeted therapies in trials - a few are in clinical trials.

[Hope59 in reply to Tall_Allen]

Have you heard about protoxin?

[Tall_Allen in reply to Hope59]

Nope

[Hope59 in reply to Tall_Allen]

I can’t find anything else on it. Maybe still early early days

[Tall_Allen in reply to Hope59]

Here are a few of the many in PSMA-targeted lab tests and early trials (aside from radiopharmaceuticals, and CAR-T and BiTEs);

pubmed.ncbi.nlm.nih.gov/299...

ncbi.nlm.nih.gov/pmc/articl...

pubs.acs.org/doi/abs/10.102...

ncbi.nlm.nih.gov/pmc/articl...

oncotarget.com/article/3174/

pubmed.ncbi.nlm.nih.gov/317...

pubmed.ncbi.nlm.nih.gov/317...

ncbi.nlm.nih.gov/pmc/articl...

clinicaltrials.gov/ct2/show...

It's a very active area of research - many years from any drug approvals (which is why I never post this sort of thing).

[TheTopBanana in reply to Tall_Allen]

Thank you for the links! Even it might be years from now, I still find comfort in what is happening in the reseach field, you never know - many men here have been alive longer that their original doctors told them and might be benifiting from this is the future, including my father. I like to think that.

[Tall_Allen in reply to TheTopBanana]

If you go to clinicaltrials.gov and type in "prostate cancer Stage 4" it will probably return thousands of ongoing clinical trials. Most of them will come to nothing, but hopefully, one or two will result in an important therapy.

[tango65]

Protoxin is not a particular product, it is a substance which is transformed in a toxin ( a poisonous substance produced within living cells) when is metabolize by a cell. There are many protoxins.

biotechterms.org/sourcebook....

[dmt1121]

Sounds like a potentially amazing treatment.....once it gets through FDA trials. Good find!

[GreenStreet]

Very interesting. Thanks for sharing

[depotdoug]

Well this is amazing modern medical technology at the speed of light. I like the terminology or description’ Protoxin is like a mail order bomb letter specially tagged with killer lethal action once that ‘mail order bomb’ finds its Cancer laced PSMA cells in our human bodies.

Brilliant study Johns Hopkins.

[Hidden]

🤞🏻Hope for this to be a game changer.

[j-o-h-n]

Sign me up for the first special delivery..........

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 08/05/2020 6:11 PM DST

[depotdoug in reply to j-o-h-n]

Me 1st j-o-h-n. I'll drive or run to the Clinical Trials medical site to get in line. Time for some pre-planning for my trip.

[j-o-h-n in reply to depotdoug]

Okay, after me your first...........

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 08/06/2020 2:34 PM DST