PSA dropped to .4, scans show no progression with 2 mets to ribs not showing. Also Alkaline Phosphatase down to 138. My MO is very pleased with results. So am I.
Talapro2 8 weeks later: PSA dropped to... - Advanced Prostate...
Talapro2 8 weeks later
Thanks for sharing these great results .. I remember when you first came on line here...It a battle royals with pc ...Finally a bit of respit for he and you . we can’t ever lay back and ignore pc completely ... now the goal is to keep it away for many years ..Take a deeeep breath, and live well....Scott🥳
Thanks Lulu700. Yep, things seemed so out of control when I first joined. But with some help, some from this sight, and a refocus of what really matters I'm in a good place. This clinical trial is getting results! Hope you are doing well...Mark
I’ve been clear over four years now and I’m also on a trail drug . Keep rolling Mark ........peace and improving health to you .. Scott
That is great news. I didn't know anything about Talapro so I looked it up and learned that it's a novel PARP inhibitor that is good at killing cells that have DNA mutations that force them to rely on PARP to repair DNA and survive. One source said that 20% of PCa patients have the DNA repair mutations that force them to rely on PARP. It could be a real game changer for those patients.
Do you know yet if you were on the PARP drug + enzalutamide, or just on placebo + enzalutamide? Even if you're on the placebo, you're still doing very well. It means you have an excellent response to enzalutamide - also a good thing.
Best of luck.
Alan
Fantastic news, great result. I signed up today for prescreening for genomic testing for DNA repair genes from tissue bisopy. If accepted, I will go into a phase 3 randomized, double blind, placebo controlled study of Talazoparib/Placebo and Enzulutamide. I am hoping I am accepted.
Same trial I am on. So far great results and the side effects have been minimal. Hope you get in so we can compare notes.
This is great news! Thank you 🥳🥳🥳
I pray it works well and keeps you on the. Topofthemountain.🙏
Thank you Lulu700
Good news... happy for you..... (Maleko = Hawaiian for Mark?)....
Beat those tiny little monsters.........
Good Luck, Good Health and Good Humor.
j-o-h-n Thursday 11/21/2019 6:54 PM EST
Make sure that you don't change your name to Malaka if you ever decide to visit Greece.....
Keep on smacking.....
Good Luck, Good Health and Good Humor.
j-o-h-n Friday 11/22/2019 11:42 PM EST - JFK assassination 1963