xzandia and lupron

[ken12491]

would there be any benefit to use both at the same time? thanks..

[Tall_Allen]

You have to use Lupron with Xtandi.

[tallguy2 in reply to Tall_Allen]

Agreed!

[ken12491 in reply to Tall_Allen]

Thanks, I didn't know that - I thought you used xtandi when lupron failed to work anymore.

[Tall_Allen in reply to ken12491]

"Failed to work" is not exactly right. The cancer will eventually become "castration resistant," which means there is progression in spite of castration levels of testosterone. When that happens, even the slightest amount of testosterone and other androgens can activate the "upgraded" androgen receptors. It is more important than ever that ADT be continued.

[ken12491 in reply to ken12491]

Allen - hope your friend is ok -- I start my chemo on Tues - docetaxel. once every 2 weeks:

Is that the normal regime?

PSA is 1.75 now..

Is the goal to get to non-detectable PSA? - I'll ask of course - But where does one draw the line on rounds of chemo? Or you can't draw a line if you want to have the best outcome?

Did the cold capping help him much - I'm going to use it..

Thanks...

[rococo in reply to Tall_Allen]

If xstandi alone is doing the job why do you have to add Lupron and go on another antiandrogen when it fails, saving adt which may take yrs as it has for me. Rocco

[Tall_Allen in reply to rococo]

see above

[larry_dammit]

If you mean Xtandi and lupron that is what I have been on the last 34 months. PSA. Is <0.05.

[Parscore in reply to larry_dammit]

How are your side effects. I think I will have to make a similar decision rather soon. Currently on Firmagon and Doctor wants to add zytiga, current PSA is on the rise..

[larry_dammit in reply to Parscore]

My dad is on zytiga ,we have had to stop for now, he was having dizzy spells when he got up, and constipation. Raised blood pressure as well. Dad is going on 88 and stage 4 with Mets in his hips. Weakness there. Not sure that’s what causes it or old injury. Anyrate after a year on it he has stopped for now , 😢 PSA rising