I've been reading the blog by Joe Tippens and went to Petmeds to order my month supply online. **pic is a picture of me taken by my partner after starting...LOL (not really it's our puppy, Sparky)
Sounds TOO good to be true...but sounds easy enough to try....Bark Bark...so I figured I'd give it a shot. Has anyone else "barked up this same tree"??. It's readily available and reasonable....and except for the side effect of barking...has few others with most people.
Sparky approves! (although he's on a much more expensive monthly single pill for worms and fleas...)
gJohn (would love to hear stories)
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I wonder if this works via the same mechanism of action as the research being conducted in Norway re: anti-parasitic medication? Albeit for humans rather than animals. I will check out the blog. Looking forward to hearing how you fare.
An another note, my vet in the U.K. used to give himself the same vitamin B12 injections that he used on his animal clients. Offered me one once but I was too skittish to accept although intrigued. He insisted that it was the same product that I got from my GP.
Is your husband still taking the BIRM? I'm on it now for a few months and my energy level has gotten a little lower (it seems like)....my PSA Has not been improving...rising very slowly, but scans look better. How are his doing?
Yes a he is still on the industrial strength but is feeling the same - initial surge of energy stabilized then wore off but he is still taking it. PSA was all over the place - took a dive on Taxotere for 3 months then spiked so switched to Jevtana and now it’s in a downward spike. I am trying to reach out to the Dr who invented BIRM for a consult to see if he are dosing properly based on his stats.
I emailed the Dr in Norway asking him about Fenben - he always replies quickly. Will be curious to see what he says.
Thanks Emily....can't wait to hear what he says. You seem really on the ball. Your husband is very lucky! My partner lets me be my full-time "caregiver/researcher/cook/housekeeper/launderer/financial planning consultant/etc"...but he does, at least, offer "moral support"...LOL.
Thanks John - I try. It infuriates me sometimes that he isn’t more proactive but I tell him that his full time job is getting better. I really wish he would come on this site and open himself up to the amazing support here but alas he is English to the bone and just can’t do it.
I had a slight head start on him as was raised by a “health fanatic” mother. We juiced every day growing up and were the neighborhood freaks - this was way before it was trendy! Interesting how that has changed though as now all the friends who scoffed at my health strategies over the years are asking how I stay healthy. Was good training for this. Found that most doctors I called - all over the world - would take my call or answer emails and give actionable advice if I asked the right questions in the right way.
But 6 years on all I know is that we have to stay vigilant and never get too comfortable!
Thanks for all your informative posts. Particularly about the Petmeda. I have placed an order just in case we decide to do it!
Do you have the name of the trial in Norway? The Swedish Health Ministry studied men with Prostate cancer and noted that those who took a Cholera Vaccine (Dukoral) had a better overall survival time than men who did not. Dukoral is anti-parasitic medicine, so maybe there's something to the off label use of these type of meds.
Will post a link to the article. The trial hasn’t yet started (as the article had mentioned). I reached out to the principle investigator and he said they are still trying to determine the exact drug before proceeding to a trial)
Professor Kalland (MD / PhD who is leading the research) emailed me back saying that the current generation of NZT isn’t ready for a trial and they are working on a next generation of a more potent version.
BTW - it is HEROIC that you are your own caretaker/researcher/cook/housekeeper/launderer/ financial planning consultant. Don’t know how you do it. My husband says I am doing the heavy lifting but the reality is that the cancer patient is. So I really applaud you for doing double, triple, quadruple duty. 👏
thanks Emily, but by staying busy ...I also run our online Ebay store. Doing all the photography and listing AND negotiating AND logistics with Movers to have things picked up and delivered all over the country...I'm too busy to have a pity party. There just isn't enough time. I've always said "idle hands are the devil's workshop"...LOL. And the "moral support" part is integral.
** We also (me mostly) take care of a former employee/friend who's on mental disability. He lives in our home...I cook for him, do his laundry...keep his doctors/psychologist appointments and drive him to them...have him exercise with us when we walk the dog AND take him to the gym 3 times a week with us...so when I don't want to go, I know I need to push myself because he and my partner really do need to keep up working out. AND, I've just come out of surgery on my hand on Wednesday for trigger fingers in thumb and index finger of RIGHT hand...and I'm right handed, of course. This has made things ....a little more "carry out/fast food" and I think they notice the difference. I was able (finally) last night to make salads for us.
Thanks John - I agree re: staying busy but must say am tired just reading about all you do! That is really quite amazing and no doubt what keeps you going. You are inspiring me and my husband as well when he hears the stories (second hand of course.)
I read Tiggen's blog with interest - am so curious to see what Professor Kalland in Norway has to say about it.
I take mebendazole (2 x 100mg daily) for a month, every other month, alongside metformin and atorvastatin - it's part of Care Oncology's protocol, where it alternates monthly with doxycycline.
As I understand it, mebendazole is a similar compound to the one in your doggy pills...
I have kept on with it after starting SRT and ADT even though there's no way to monitor effectiveness in the zero PSA setting - it's no big deal, just a couple more pills to chew on.
I started the CareOncology program in mid-Sep 18, and I believe I commenced with mebendazole - since it's alternated monthly with doxycycline, I am just a couple of weeks into my fifth month. I started at one tablet (100mg)/day and they advised me to double this to 2 x 100mg (morning and night) in December. Their expectation was that I might see a PSA impact after ca. four months - and indeed, I had my first (albeit small) PSA drop in January, just before commencing the ADT leading into ADT. I am keeping the CareOncology drugs up in the hope of giving any stray PCa cells a very hard time metabolically...
OK, well, I guess I'm crossing the "offering advice" threshold here, but...
I don't advise you keep COC in your back pocket. It takes months to start working, and they don't advance it as curative - rather as something to be used alongside any more directed treatments that are available... and that makes sense when you dig into it a bit and recognise that it is damaging the PCa at a metabolic level rather than addressing it in a direct fashion. So... I wouldn't sit on it too long as an option... it's pretty harmless stuff, I suspect, by comparison with what you're dealing with and the treatments you've had to use thus far.
As to concerns with doxycycline for a month - it's 100mg/day, which is not much. To put it in context, I worked in the mining /oil & gas game for many years and we routinely put staff, me included, on long term doxy when sending them to south asia or anywhere else where malaria was endemic. Low-dose doxy is frequently prescribed to long term travellers as prophylactic for travellers diarrhoea... So when my Australian GP looked at the COC protocol (which she administers under their instructions since it's easier than having drugs sent from the UK), she suggested we just run the doxy 100% of the time. I asked COC about this and they said they were concerned about long term impact on the biome - so we have stuck with their approach of alternating with the mebendazole. I lived in the UK for 7 years and during that time formed the impression that attitudes to several "standard" drugs used there are different to Australia and visa versa - doxy seems to be one where Australia has a more relaxed attitude.
Anyway, I have been doing this for 8 months now with no obvious negative impact I can see... doubtless my biome has been rearranged in some way, but I am a very heavy veg/fruit eater so I just hope the little blighters breed faster than the doxy knocks 'em off! Sounds a bit blasé, but it's not... there seem to be good reasons to give doxy a crack: DOI 10.1038/s41389-017-0009-3
Thanks John, I plan to keep doing the same stuff for a while yet...
CareOncology had me double the mebendazole late in 2018 and I got my first and only fall at the next PSA reading. Only by about 0.005, so could have been noise. But the scientist in me can’t help but notice it was the ONLY fall I saw in a parameter that otherwise increased monotonically for 8 months - could mean something...
Anyway, ADT has put paid to further checking for now... and just maybe, for good!
For what it’s worth, I reckon you could do worse that give it a shot - CareOncology reckon they’re seeing good results.
There's not a much published literature on this use of fenbendazole, but a PubMed search did turn up a few hits noting anti-cancer activity.
Joe Tippens takes one gram of fenbendazole for 3 days each week. It's not very toxic, in lab animals the LD50 is about 10g/kg. So a 1-gram dose in an adult man should be safe.
There is one paper with evidence of synergy with 2-DG.
This looks to me like something reasonable to try: low chance of harm, low cost, unknown chance of benefit, but some reasons for hope.
I don't know about interactions with modern drugs, no one has published anything that I could find. I'm starting an ADT vacation period, and plan to establish a baseline PSA and PSADT before I try 3 months of fenbendazole using the Tippens protocol. Note that Tippens also takes a largish dose of CBD oil, enhanced bio-availability curcumin complex, and a vitamin E complex.
thanks....good luck with the "Joe" protocol. I hope to be starting it soon as I have placed my order with "petmeds"...LOL..every time I say this is makes me laugh.
I also take Curcumin but no CBD...found it made me feel weird...but I take Concentrated BIRM. I also take ginseng, a mushroom combo pill(with each meal), and eat lots of cooked mushrooms....hoping for a magical synergistic approach from this and my "regular human meds" that will help make my PSA go drastically downward (for once). It's never been real high, but it's only dipped below 1.0 ONCE and for a brief moment! Back just a little over 2.0 now. Currently "just" on Lupron and Xtandi and Xgeva....and I mean "just" in a crazy sarcastic way. Those 3 are enough to do a lot of us in. I'm doing very well (side effect wise) which I must credit to the BIRM...before I started it...I was only on Xtandi for about 3 months before I was asking to lower the dosage.
Was thinking about the book "The Miracle" by Irving Wallace. It puts the term "miracle" into some wonderful and inspiring perspective.
Re: laughing every time you say “PetMeds” - my vet in the U.K. actually gave me a bottle of animal vitamin B12 along with supplies to give myself the injection. I kept them in the medicine cabinet and noticed that anytime we had anyone over for dinner my husband would hide it! Never had the courage to use it. Every time o got close would start thinking about that movie “The Fly” 😂
There was a time when it was hard to get some of the mineral supplements I was getting in a weekly IV. I ordered them from a veterinary supply company.
After I had been on the drip for an hour or so, the IV nurse came in to check on me.
"Doesn't it bother you that the label says this is for use in goats?"
FBZ is similar in action to mebendazole and works by disrupting microtubulin formation during cell division cycle. As mentioned above, it is one of the many drugs involved in repurposing for cancer movements/protocols due to its potential biological action and limited pre-clinical data. The problem is as always in details. The bioavailability is extremely poor. It's basically don't get absorbed much into plasma and just passes through the GI. Which for the indeded purpose (de-worming) is a fantastic property, but is not good for cancer treatment since we want to deliver it to the very cells. Logically, it has low toxicity (cause not much gets into the blood) and one could consume 1000s of mg without noticeable side effects. Plus absorption varies wildly between individuals and foods, generally improving with fatty meals on empty stomach (not a pleasant combination).
So this guy died from a broken neck after taking fenbendazole for six months. It seems he was lying on the couch licking his balls when he fell off the couch and broke his neck...
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Anyone taking METANX?
Axumin PET Scan Results
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