Chemo ?: Two more rounds to go (Friday... - Advanced Prostate...

Advanced Prostate Cancer

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Chemo ?

Zetabow profile image
13 Replies

Two more rounds to go (Friday next session), progress has been good considering the extensive mets, my PSA down from 1386 g/l to 0.4 g/l in 5 months. Doctor said after this Chemo I should be good for around 9 months before needing another round.

Do they just keep giving Chemo until it stops working or the body cannot handle it anymore. How many times can you have Chemo?

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Zetabow profile image
Zetabow
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13 Replies
GP24 profile image
GP24

You can repeat Chemo until you become resistant to Docetaxel. However, I would continue on ADT now. This could keep the PSA value low so you do not need a Chemo in nine months.

Zetabow profile image
Zetabow in reply toGP24

Thanks, although I managed quite well, I can see a point where you maybe cannot physically or mentally handle it anymore. I was in a bad way with pain last Nov and the Chemo has helped quite a lot, I still have pain but it's greatly reduced.

GP24 profile image
GP24 in reply toZetabow

I suggest you try to get into the VISION trial. However, they seem to have stopped to accept new patients since too many patients in the control arm insisted to get the new treatment instead.

visionclinicaltrial.com/abo...

Zetabow profile image
Zetabow in reply toGP24

I asked at the start if they had any trials available, he said no, maybe living in a small country with 1.3m population has some disadvantages.

GP24 profile image
GP24 in reply toZetabow

Here are the locations where you can participate in this trial:

clinicaltrials.gov/ct2/show...

Zetabow profile image
Zetabow in reply toGP24

Thanks for the info (always good on this site), as I suspected Estonia isn't on that list

GP24 profile image
GP24 in reply toZetabow

However, Sweden is not that far.

Tall_Allen profile image
Tall_Allen

That was a great response. It's usually 6 rounds at a time (once every 3 weeks). It can be continued (with breaks) until it stops working. When Taxotere stops working, there's Jevtana.

tallguy2 profile image
tallguy2

You've had a great response to Taxotere. Congrats! You can keep trying Taxotere as a "re-challenge" or move to platinum-based chemo (but this hasn't been FDA-approved for prostate cancer). Please keep current with your scans. If there's bone metastasis you have options like Xofigo.

JamesAtlanta profile image
JamesAtlanta

Congratulations on the great response!

James

dockam profile image
dockam

That's a great response! After 5 Taxotere sessions, my PSA was still in teens(840 at Dx), so MedOnc asked tumor board if they'd give me more and no one assented. He told me he would continue chemos until PSA plateaus or I say "stop" I had nine more, 15 total and only got to 0.7, but had a nadir of 0.1 the next year.

j-o-h-n profile image
j-o-h-n

I guess as long as you can handle it. Good Going 🤜🤛 fist bump....

Good Luck, Good Health and Good Humor.

j-o-h-n Tuesday 04/09/2019 8:01 PM EDT

Zetabow profile image
Zetabow

last round (6th) yesterday all went well, changed my pain meds and Thighs and Ribs feeling better for the moment at least.

He showed my first PET scan (I will have another in six weeks), he basically said the Mets are on just about every bone in my body, kinda lucky I'm only getting pain in two places.

With such extensive mets in my body, does it increase the chances of spreading to other organs more easily or is it the Lymph system that's more likely to carry it to the organs?

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