Not rising psa

[Annie1373]

I have read this article (below)and wondering if men with genitics mutations who have prostate cancer and also men with visceral metastasis don’t experience significantly psa rise as others ,while their disease progress... Just want to know your opinion .sorry to ask too many questions today...

targetedonc.com/publications/

targeted-therapies-cancer/2018/2018-april/dramatic-response-to-olaparib-in-a-patient-with-metastatic-castration-resistant-prostate-cancer

[Tall_Allen]

What genetic mutation does he have?

[Annie1373]

He has mutation In BRCA2 and his mother had breast cancer too

[NPfisherman in reply to Annie1373]

Recently, pjoshea13 posted on a parp inhibitor effective in BRCA 1/2 mutations...

healthunlocked.com/advanced....

Hoping for your Dad to feel better soon

Fish