Radiation together with ADT vs ADT first than radiation

Any proven that beginning with ADT to have PSA as low as possible before radiation has a better outcome? In our case, no need to shrink prostate size.

[Dayatatime]

PSA is a biomarker and in most cases it can give a fair indication of when cancer cells are active. ADT weakens cancer and makes it more susceptible to localized treatment whether it's before, during or after. The answer to your question is do both. You get one shot at this and make it count. Neoadjuvant ADT is 8 weeks, adjuvant 6 months to 2 years depending on PSA going into it. I'd say that's a small price to pay considering your goal is to live a long life.

When treating prostate cancer at the advanced stage our hope of one knockout punch unfortunately is gone. Our arena is keep jabbing, swing and hope you connect and put it down. The earlier the better while you are strong and cancer is weak. Beat it down and give yourself the best odds when you give that hard hit.

Ron

[Tall_Allen]

Yes - two months of ADT first is usually enough. It sensitizes the cancer to radiation.

[cesanon in reply to Tall_Allen]

How about following radiation?

[Tall_Allen in reply to cesanon]

That depends on the situation. With metastases, it has to be long-term.

[cesanon in reply to Tall_Allen]

By long term do you mean 1 to 2 years or 5 to 7 years?

[Tall_Allen in reply to cesanon]

Can you please say which situation you're talking about?

[cesanon in reply to Tall_Allen]

I was just thinking of a generic situation of radiation treatment for either metastatic or non metastatic cancer.

As I have metastatic cancer that was treated with radiation at Dattoli (3 lymphs & 2 bones) perhaps I was subconsciously thinking about that scenario. But I consciously intend to limit the question to that.