Metástasis or Osteoarthritis?

Anyone ever been misdiagnosed? Is it possible? Lupron,Casodex,Zytiga, Prednisone does cause bones to deplete. Just a though

[Tall_Allen]

You mean bone metastases, I assume. Prostate cancer bone mets are typically "blastic" rather than "lytic." Blastic means there's is too much bone tissue, lytic means there is too little. A bone scan/CT picks up areas of bone overgrowth (blastic) - which may also be due to irritation (like arthritis or previous injury). If they are true metastases, hormone therapy will reduce them. If they are not true meastases, hormone therapy will have no effect. So giving hormone therapy and seeing what happens as a result is diagnostic for metastases.

[drsridhar53 in reply to Tall_Allen]

Thanks for the information Tall. Does Ga 68 PSMA scan pick up anything other than secondary Prostate Ca which has spread. Thanks

[Tall_Allen in reply to drsridhar53]

It does pick up a few other cancers, and accumulates in the salivary glands and passes out through the kidneys. It picks up about 90% of all prostate cancers (the cancer has to be PSMA-avid).

[RonL in reply to Tall_Allen]

I’ve had rheumatoid arthritis for over thirty years, the doctors were able to distinguish the difference between arthritis activity and bone mets in my scans with little difficulty.

[Hidden]

To make things easier for the Doctir raging the scan, always take a base line scan and then a scan at each procedure. Sound like a lot of scans? Consider that in my first seven years I had 21 nuclear bone and soft tissue CT scans and then smother set in six years later

GD

[Stegosaurus37]

It's a good question. I'm 76. Is something a residual side effect of the taxotere, a side effect of the Xtandi, the cancer, the fact that I'm 76 or some combo thereof? Pain in my left hip; last bone scan did not show mets there so concluded it was arthritis. X-rays show severe osteoarthritis to both hips. Yet naproxen, while improving the situation, didn't completely alleviate it. It's a puzzle.