CCS1477

[dress2544]

Hi everybody

I have read about the above treatment ccs1477 in a prostate cancer journal. I hope someone in our forum can give a better idea about this treatment.

[wrando]

sounds interesting...cellcentric.com/press-relea...

[Tall_Allen]

That clinical trial has not begun, but there are a couple of similar medications in clinical trials that are currently recruiting:

clinicaltrials.gov/ct2/show...

clinicaltrials.gov/ct2/show...

[dress2544 in reply to Tall_Allen]

Thank you Tall Allen for the information.

[ctarleton]

These might be a couple of the precursor lab/mouse studies that led to the hypotheses that these kinds of compounds might possibly be useful in combinations with enzalutamide, PARP inhibitors, and/or platinum-based drugs where "resistance" mechanisms to treatment may be involved.

cell.com/cell-reports/fullt...

ascopubs.org/doi/abs/10.120...

It would be wonderful if something eventually pans out in human Phase I/II/III Clinical Trials to provide high level evidence that these types of combination treatments might work better or longer in advanced prostate cancer treatment.

Charles