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Advanced Prostate Cancer
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Newer Antiandrogens & Emerging Therapies Targeting a "Watchful Waiting" and Resistance Population

This was published a year ago, Feb 1, 2017, so I wonder if any of the possible new treatments listed have become more promising. Perhaps something here will pop out a someone on this site. It's over my head. I posted this link in a response to Dan's post about Proxalutamide, and thought maybe posting again, as a new topic might dig something else up.

Prostate Cancer - Newer Antiandrogens & Emerging Therapies Targeting a "Watchful Waiting" and Resistance Population

giiresearch.com/report/madv...

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With all these cutting drugs it is really funny to see Modified Citrus Pectin probably a 15 year old supplement. Dr. Myers said like a bad cold this pops up every few years when Life Extension does a promo on it. Myers said 100's of his patients tried it and except for really bad gas MCP was worthless...he never saw one case where it did any good.

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Gus, that was just my thought too, Then I remembered that Nalakrats gave me a lot of information on that 3 or 4 months ago. Made me think.

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Patrick said at one time Thorne Research made one that had a small molecular weight that could have possibly had some merit but they discontinued it. Myers said no benefit and I tried it for a few months and all I got was an upset stomach. My judge has always been the market place...look at the commotion PCSPES made when it lowered PSA...any product that stopped or slowed metastasis would be the holy grail. MCP has been around for more than 10 years, 27000 guys a year die from PCa and the original tumor doesn't kill you, it is the metastasis that does....all these powerful drugs and PCa finds a way around them...think about it...all these guys dying and most people never heard of MCP...if it really stopped metastasis it would be all the rage...everybody would know about it and be using it

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Gus, what do you think is Life Extension's motivation for their promotion?

jal

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The usual..they sold it...Pectasol is around $100 a bottle with a wholesale price of $35..not a bad reason to promote it

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Thank You for posting this, I am really glad we have this list saved where we know where it is for future research.

Dan

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The novel hormonals I still have in my file are: AZD-3514, TAS-3681, ODM-204, Relugolix, TRC-253, and VT-464. Several hormonal agents were tested and found to be ineffective, and other trials have been terminated for various reasons. The ones that bit the dust include: ASN-001, EPI-506, EZN-4176, TOK-001, LFA102, Orteronel, TAK-448. Capesaris tested well, and they fixed the clotting problem, but I think GTX has dropped it.

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TA,

do you have a supplement protocol that lowers PSA and or increases doubling time

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No. The only supplement that that proved useful in a randomized clinical trial is sulforaphane. And it should be taken with some raw broccoli to replace an enzyme lost in processing. Supplements are drugs - some are harmful, some are not, most have been proven ineffective when they were tested in randomized clinical trials.

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that is what Dr. Myers said...supplements are dirty drugs...some where out there, there has got to be one or a combination that will lower PSA and or increase doubling time..I have been searching for 10 years with no luck

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I don't know about supplements defeating PC. I do think that supplements for bone health and heart health and so forth are useful. I've noticed that I can dial back on one of my heart meds and remain free of atrial fibrillation episodes when I take CoQ10, L-Arginine and L-Taurine. Glucosamine-Condroitin for joint health seems to work too. I had knee pain while driving when I couldn't stretch out my long legs. After I started taking that supplement that problem went away.

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The drug companies have got to move beyond anti-androgens with each new one buying 6 months after the previous failure of the old one at 10,000 a bottle...the answer is a vaccine IMO

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supple mints, my favorite are vodka flavored.

Good Luck and Good Health.

j-o-h-n Monday 03/19/2018 5:14 PM EDT

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The list of antiadrogens geting longer. Is hoping for a more durable response from them wiishful thinking? Each saying 3 to 10 times stronger which means if you got 7yrs out of casodex you get 20 to 70 yrs more. Ha. Ha. Rocco

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