PSADT: PSADT<1month! from March till... - Advanced Prostate...

Advanced Prostate Cancer

22,373 members28,135 posts

PSADT

Alinur profile image
6 Replies

PSADT<1month! from March till now PSA rose from 0 to 0.7.cancer found in pelvis bone(MRI).The spot was not there in January(very aggressive).Can this be the only source of this aggressive PSA Soar or more cancer is to be found!

RP in 2011,SRT+ ADT.No therapy since September 2016!

Thanks guys!

Written by
Alinur profile image
Alinur
To view profiles and participate in discussions please or .
Read more about...
6 Replies
ctarleton profile image
ctarleton

You might consider getting monthly PSA tests to keep a closer watch on your PSA trends and doubling times.

mskcc.org/nomograms/prostat...

You might also ask your doctor about if/when you might get another type of scan for further evaluation of your disease status. Names like NM Bone Scan, PSMA PET, C-11 Choline, F-18, Axumin, etc.

Some related overview info is here as a starting point for further research and discussion with your doctor, or referral to other specialists:

pcnrv.blogspot.com/2016/12/...

Finally, you might begin your own research by Googling the search term "oligometastatic prostate cancer"

google.com/search?q=oligome...

Charles

Alinur profile image
Alinur in reply toctarleton

Charles,

I had 2week PSA since March and the trend was monthly doubling!Had MRIs which showed that 12mm acetabullum met.thanks for the sites.

wifeofvet profile image
wifeofvet in reply toAlinur

anyone ever suggest you have that spot radiated??? my husband has the most aggressive form...diagnosed with bone mets to ribs at the same time as prostate biopsy came back positive at age 57. he had major exposure to agent orange in Nam. his PSA went from zero to 1 to 77 in two six month interval tests before diagnosis, and then a gleason score of 10 at diagnosis. as mets popped up in shoulder and pelvis and long bones, they spot radiated to slow progression. he's failed every drug there is, and every chemo..and today is the 12th anniversary of diagnosis. his prognosis at diagnosis was a 1% chance of surviving three years.,,before abiraterone and enzalutamide came on the market.

arrangements are being made for him to take Xofigo next week. unfortunately, he's no candidate for clinical trials because he also suffers from Stage IV laryngeal cancer...the second most common cancer from agent orange exposure.

Break60 profile image
Break60

Fast psadt is definitely a troubling sign. I assume it happened after you stopped ADT . What was your PSA history since RP and what was your pathology? I've had a similar fast doubling time problem due to Gleason 9 and poor pathology. I've had 3 recurrences. In prostate bed, in pelvic lymph nodes found by MRI and in femur found by axumin ctpet scan. So I'm back on ADT, on xgeva and had SBRT to the bone met. PSA back down to .3 from 2.3. All I can say is that my PCa is systemic and I just need to keep fighting it systematically and focally. You're probably in a similar boat.

Bob

Alinur profile image
Alinur in reply toBreak60

Bob,my Gleason was 3+4=7 & T3b. I never allowed PSA to exceed 1 during HT vacation.MRIs never showed anything.But this time at PSA=0.6 MRI found a suspicious area in the iliac bone.It was not there in my last MRI.PSA is now rising faster than other times!

I have severe Osteopenia and degenerative disease in almost all the skeleton.That is why bone scan is not reliable in my case.

I hope to have PETCT soon.

Bob, how did SBRT worked for you? Did it eliminate the met?

Thanks

Break60 profile image
Break60 in reply toAlinur

Alinur

I'm pt3b too but 4+5=9. You know that pt3b is not good. My PSA went to .3 after RP then I had SRT. It then went to 1.2 and I had MRI which found two hot iliac nodes so I had all pelvic nodes radiated with75 grays and 13 months ADT. Lastly afte stopping ADT I let PSA rise to 2.3 and had axumin scan and SBRT to single femur met. I don't know if the met is gone but I read that SBRT doesn't necessarily kill the cancer in bone but knocks the heck out if it. Since I went back on ADT it's hard to tell what caused PSA to decline to .3 but with my high risk PCa I can't take the chance of doing just focal treatment.

Bob

Not what you're looking for?

You may also like...

PSADT is 6 months

My PSA increased from 0.19 to 0.3 in just 6 weeks. My MO is scheduling a PSMA pet to see if the...
old64horn profile image

Just diagnosed with prostate cancer.

08/2024 PSA 8.7, biopsy found 10 of 12 to be Gleason 9. F18 PET scan found it has metastasized....

Told to listen to his body

At last appointment our question was “ how do we monitor his cancer” and we were told to listen to...
Yecart1977 profile image

Advanced prostate cancer recurrence

Hi every one,starting external Radiothereapy therapy?currently my PSA reading is 0.13 considered...
Nuray profile image

Could This Alternative Regiment Be Decelerating My PSA?

Between Summer of 2021 and Summer of 2023--two solid years--my PSA went from 11.5 to 15.3,...
back2health profile image

Moderation team

Bethishere profile image
BethishereAdministrator
Number6 profile image
Number6Administrator
Darryl profile image
DarrylPartner

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.