We read a lot about low TET (Testosterone) and men with PCa (Prostate Cancer) suffer thru this condition. After a RP surgery we all want to 'get back to normal.' All of us have been exposed to TRT (TET Replacement Therapy), both promotion and promise. But, what is Low TET? How does TRT relate to this diagnosis? What are the goals we realistically need to have if and when we go the route of trying to replace our TET? The Institute of Human Anatomy has the best discussion I have heard on this subject. TRT for the sake of TRT is not good practice. Recovery of QOL and most importantly reversal of symptoms should guide us!
Not discussed here is the safety of TRT for men who have had RP; this is a hot button subject. I have posed a lot on this issue in my blog, so if you are interested in this find the ART (articles) I have already uploaded. Generally, TRT is not recommended for men who have already had BCR (PSA recurrence)...Doctors will not give you TRT if you ask for it under these conditions. But if you had surgery and have never had BCR and are safely past 5 years plus without recurrence and suffer from the symptoms of low TET, then TRT may be for you...if you follow good practice as noted above.
Here is my summary on the post from the IHA;
TET Source; Testis produce most of the male Testosterone androgen we need
Adrenal Cortex; 5% of the TET comes from here (continues after a RP surgery)
Low TET Levels; normal ranges 300-1000 ng/dL
Low TET Diagnosis; 2 tests different days done before 8am with TET <300 ng/dL
Signs n Symptoms Low TET; long list including reduced muscle mass, obesity, depression, decreased libido and ED, plus a lot of other symptoms.
TRT Therapy; TET replacement therapy needs to have both Low TET and Symptoms
TRT Without Testing; 25% of men get TRT without getting a blood test. Not recommended.
AUA Goals TRT; American Urological Association goals are to get men diagnosed with Low TET to 450-600 ng/dL
Continued TRT Treatment; AUA stops TRT when TET reaches the target range and symptoms improve. If no improvement in symptoms occur AUA recommends men stop TRT.
Retest for TET; 50% of men never retest their TET levels after TRT. Monitoring not being done.
Symptom Improvement; true goal for TRT. Taking TET for the sake of taking it, without monitoring and without linking treatment to symptom improvement is senseless (possibly health threat).