How unusual - a Plain English summary is included!
I know we are primarily about human thyroid issues, but this will be of interest to a considerable number of members who are involved with dogs. (Perhaps there will be a cat version sometime?)
Research
Open Access
Published: 24 May 2022
Breed distributions for diabetes mellitus and hypothyroidism in Norwegian dogs
Plain English summary
Diabetes mellitus (DM) and hypothyroidism are diseases that are caused by dysregulations in the hormone system and are categorized as endocrine disorders. Diabetes mellitus and hypothyroidism are chronic diseases and may strongly affect the quality of life for the affected dogs if the treatment fails. One of several acknowledged mechanisms behind both diseases are associated with autoimmunity, where the immune system attacks and destructs the respective hormonal gland. Previous studies have investigated other possible factors that might influence the development of the diseases, including sex, breed and weight.
Breed differences were discovered for DM and hypothyroidism in the present study. The most susceptible breeds for DM were the Australian terrier and Swedish lapphund, whilst German Shepherd and Golden Retriever were the least susceptible. Schnauzer and Eurasier where the most susceptible for hypothyroidism, while Rottweiler and Dachshund were the least susceptible. There were indications of an opposite relationship between the two diseases in some breeds as some of the breeds showed high susceptibility for one of the diseases, and low susceptibility for the other disease. Other breeds seemed to be susceptible for both diseases. This information supports a multigenetic complex inheritance and could be of importance in future genetic studies of these diseases.
Open access to full paper:
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