Chronic Fatigue Syndrome?

[shaws]

I may have posted this in the past, but for those who've not seen it the link is below:-

dynamicchiropractic.com/mpa...

[Silly]

wow it just needs my name as the patient

[Justiina]

I started think about that faulty T3. I just read article written by a doctor who had ended up starting lio on patients who were poorly on levo.

The thing that was interesting that on levo they could have higher ft3 than on T4+T3 but still the wellbeing was better. Like patient could have values that indicate good conversion on levo only. Yet after starting T3 the ft3 could be 1 point lower but patient felt better and continued to feel better which exclude placebo as patient lost weight and wellbeing was very good years after. Placebo wears off.

So I started to think that if it's not t4 converting to rt3 causing the issue could it just be that regardless of good test results on levo only the t3 is faulty or less bioavailable so it just sits in your blood but never enters the cells.

That would sort of explain why some with good conversion just never feel good and everything else is ruled out. It could be either having enough T3 at one dose that would enter the cells where on levo only good level of ft3 is not potent enough. Or dosing T3 different times of day would mimic one's biological rhythm far better.

Just made me wonder as that doctor had got surprised too, it was not just one patient, was many more. With these patients they had tried many different things first like optimising vitamins and other hormones so it took long time before they ended up trying lio.

So it would simply underline the fact that medication should be tailored individually. These people didn't have huge difference between tsh and ft4 either on either t4 or t4+T3.

Dunno. It just crossed my mind that maybe that is why many fails on levo despite very good ft3. It just less potent/or never enough.

[shaws Administrator in reply to Justiina]

One of our Advisers and his team as well as other Researchers have found many feel better with a combination of T4/T3 but the Endocrinologists appear not to take any notice of Research and, even if we are very very ill, they deny it is anything to do with the thyriod gland as our results on levo are 'in range'.